Women are more subject than men to atrophy of the heart.
 Oliver Wendell Holmes Sr., The Professor at the Breakfast-Table (1860). copy citation

Context

“How many women are born too finely organized in sense and soul for the highway they must walk with feet unshod! Life is adjusted to the wants of the stronger sex. There are plenty of torrents to be crossed in its journey; but their stepping-stones are measured by the stride of man, and not of woman. Women are more subject than men to atrophy of the heart. So says the great medical authority, Laennec. Incurable cases of this kind used to find their hospitals in convents. We have the disease in New England,—but not the hospitals. I don't like to think of it.” source