In the extreme of melancholy the self that consciously is can do absolutely nothing.
 William James, The Varieties of Religious Experience (1902). copy citation

Context

“Hope had entered into my heart, and once entered on the path, the God of Jesus Christ, to whom I then had learned to give myself up, little by little did the rest.”129 It is needless to remind you once more of the admirable congruity of Protestant theology with the structure of the mind as shown in such experiences. In the extreme of melancholy the self that consciously is can do absolutely nothing. It is completely bankrupt and without resource, and no works it can accomplish will avail. Redemption from such subjective conditions must be a free gift or nothing, and grace through Christ's accomplished sacrifice is such a gift.” source