The sensibility of some men, however, to some of the objects which immediately affect themselves, is sometimes so strong as to render all self-command impossible.
 Adam Smith, The Theory of Moral Sentiments (1759). copy citation

Context

“that the security of the God was altogether the benefit of nature, which had exempted him from suffering; but that the security of the wise man was his own benefit, and derived altogether from himself and from his own exertions.24 The sensibility of some men, however, to some of the objects which immediately affect themselves, is sometimes so strong as to render all self-command impossible. No sense of honour can control the fears of the man who is weak enough to faint, or to fall into convulsions, upon the approach of danger. Whether such weakness of nerves, as it has been called, may not, by gradual exercise and proper discipline, admit of some cure, may, perhaps, be doubtful.” source