“ His life with Joanna was rendered extremely unhappy by his infidelity and by her jealousy, which, working on a neurotic temperament, precipitated her insanity. The princess gave way to paroxysms of rage, in which she was guilty of acts of atrocious violence. Before her mother’s death, in 1504, she was unquestionably quite insane, and husband and wife lived apart. When Isabella died, Ferdinand endeavoured to lay hands on the regency of Castile, but the nobles, who disliked and feared him, forced him to withdraw. Philip was summoned to Spain, where he was recognized as king. ”