There is nothing more stimulating than a case where everything goes against you.
 Arthur Conan Doyle, The Hound of the Baskervilles (1902). copy citation

Context

“Have just heard that Barrymore is at the Hall. BASKERVILLE.
The second: Visited twenty-three hotels as directed, but sorry to report unable to trace cut sheet of Times. CARTWRIGHT.
«There go two of my threads, Watson. There is nothing more stimulating than a case where everything goes against you. We must cast round for another scent.»
«We have still the cabman who drove the spy.»
«Exactly. I have wired to get his name and address from the Official Registry. I should not be surprised if this were an answer to my question.»” source

Meaning and analysis

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