“ The condition may even go on to a fatal result should morphine be continuously withheld, but injection of even a small quantity of morphine causes these symptoms to cease abruptly. The sudden withdrawal of morphine should therefore never be practised with takers of large quantities of the drug, but gradually diminishing doses given by the physician should be substituted. For the successful treatment of morphinism, complete isolation of the patient is necessary in a place where he is supervised so that he can obtain no morphine. ”

“ The nails become brittle and the skin dry, sterility shows itself in women and sexual impotence in men. While not directly causing death, morphinism so lowers the bodily powers that the patient is easily carried off by some intercurrent malady. The sudden withdrawal of the drug from a morphine habitué is followed by a train of alarming symptoms. ”

“ Morphine is the greatest anodyne we possess, and no drug yet discovered equals it in pain-relieving power. The most frequent mode of administration is the hypodermic method, on account of the extreme rapidity with which it is absorbed. In pain due to violent sciatica relief and even permanent cure has been obtained by the injection of morphine directly into the muscle of the affected part, and in the treatment of renal and hepatic colic morphine given subcutaneously will relieve the acute pain consequent on the passage of biliary and urinary calculi. ”