“ A variety of the malady, pemphigus foliaceous, affects the whole body, and gradually proves fatal. Pemphigus of an acute septicaemic type occurs in butchers or those who handle hides, and a diplococcus has been isolated by William Bullock. The treatment is mainly constitutional, by means of good nourishment, warm baths, local sedatives and tonics. In chronic pemphigus, streptococci have been found in the blebs, and the opsonic index was low to streptococci. Improvement has been known to take place on the injection of a vaccine of streptococci. ”