1911 Encyclopædia Britannica, Volume 22… (1911)
“ Guaiacol may be obtained directly from beechwood tar, from pyrocatechin by methylation with potash and potassium methyl sulphate at 180°, or from anisol by nitration, reduction of the ortho-nitroanisol to amino-anisol, which is then diazotized and boiled with water. It melts at 28° and boils at 250°. It is employed in medicine as an expectorant. The dimethyl ether or veratrol is also used in medicine. Many other pyrocatechin derivatives have been suggested for therapeutic application. Guaiacol carbonate is known as duotal, the phosphate as phosphatol, the phosphate as guaiaco-phosphal ”
