“ In ordinary doses it greatly increases the secretion of the small intestine and stimulates its muscular coat. The gall-bladder is also stimulated, and the biliary function of the liver, so that colocynth is both an excretory and a secretory cholagogue. The action which follows hypodermic injection is due to the excretion of the drug from the blood into the alimentary canal. Though colocynth is a drastic hydragogue cathartic, it is desirable, as a rule, to supplement its action by some drug, such as aloes, which acts on the large intestine, and a sedative must always be added. ”

“ The seeds, which number from 200 to 300, and are disposed in vertical rows on the three parietal placentas of the fruit, are flat and ovoid and dark-brown; they are used as food by some of the tribes of the Sahara, and a coarse oil is expressed from them. ”