W.H.R.Rivers, Review of H. Maudsley's 'Pathology of Mind'… (1895)
“ Dr Kraepelin calls attention to the fact that the mental diseases in their early and most instructive stage of development do not often come under the hands of the physician, or if they do, are not in a condition to make exact investigation practicable, and he proposes to supply this deficiency by investigation of the effects on mental capacity of such influences of fatigue and drugs. These are not only frequent factors in the causation of insanity, but produce even in moderate amounts mental effects which are identical in nature with those of many forms of incipient insanity. ”
