“ His observations on mountain-sickness led him to conclude that it was caused by “diminution in atmospheric pressure, which operates in at least two ways—namely, (a) by lessening the value of the air that can be inspired in any given time, and, (b) by causing the air or gas within the body to expand, and to press upon the internal organs”; and that “the effects produced by (b) may be temporary and pass away when equilibrium has been restored between the internal and external pressure.” ”

“ Mr Whymper’s report was published in the Report of the British Association for the year 1869. Though hampered by a want of means and by the prevalence of an epidemic among the natives, he proved that the interior could be explored by the use of suitably constructed sledges, and thus contributed an important advance to Arctic exploration. Another expedition followed in 1872, and was devoted to a survey of the coast-line. He next organized an expedition to Ecuador, designed primarily to collect data for the study of mountain-sickness and the effect of reduced pressure on the human frame. ”