“ Its nasty taste, its irritant action on the bowel, and its characteristic odour in the breath, prohibit its use—despite its other advantages—in all diseases but gonorrhoea. For this disease it is a valuable remedy, but it must not be administered until the acute symptoms have subsided, else it will often increase them. It is best given in cachets or in three times its own bulk of mucilage of acacia. Various devices are adopted to disguise its odour in the breath. The clinical evidence clearly shows that none of the numerous vegetable rivals to copaiba is equal to it in therapeutic value. ”