R. C. Carpenter, Ventilation Standards and Ventilation Methods
“ Even if oxygen is breathed instead of air, there is no appreciable change in the percentage of carbon dioxide in the alveolar air. Want of oxygen is thus not a factor in the regulation of normal breathing. It is the carbon dioxide stimulus that regulates the breathing, although with excessive muscular work other accessory factors may come in. Thus, for instance, the barometric pressure either higher or lower than normal has a great effect on the proper regulation of the amount of carbon dioxide and oxygen, but this consideration is not important in connection with ordinary ventilation. ”
