“ In fact, we have to go back to the science of centuries ago to find a man of science of so many-sided an activity as he. His life constituted in a certain sense a protest against that specialized differentiation which, however much it may under certain aspects be regretted, seems to be one of the necessities of modern development. In Johannes Müller’s days no one thought of parting anatomy and physiology; nowadays no one thinks of joining them together. Kölliker did in his work join them together, and indeed said himself that he thought they ought never to be kept apart. ”

“ If he did much for these branches of science, he did still more for histology, the knowledge of the minute structure of the animal tissues. This he made emphatically his own. It may indeed be said that there is no fragment of the body of man and of the higher animals on which he did not leave his mark, and in more places than one his mark was a mark of fundamental importance. Among his earlier results may be mentioned the demonstration in 1847 that smooth or unstriated muscle is made up of distinct units, of nucleated muscle-cells. In this work he followed in the footsteps of his master Henle. ”

“ At the time when Kölliker was beginning his career the influence of Karl Ernst von Baer’s embryological teaching was already being widely felt, men were learning to recognize the importance to morphological and zoological studies of a knowledge of the development of animals ”