Erasmus Darwin

“ I. All the fibrous contractions of animal bodies originate from the sensorium, and resolve themselves into four classes, correspondent with the four powers or motions of the sensorium above described, and from which they have their causation.
1. These fibrous contractions were originally caused by the irritations excited by objects, which are external to the moving organ. As the pulsations of the heart are owing to the irritations excited by the stimulus of the blood; and the ideas of perception are owing to the irritations excited by external bodies. ”