Robert Lee, A Contribution to the Pathology of Phlegmasia Dolens (1829)
“ She complains of great weakness in the whole left inferior extremity, and pain along the inner surface of the thigh and leg, the trunk and principal branches of the internal saphena vein, to the ankle are enlarged, indurated, and very painful on pressure; a considerable degree of swelling exists in their whole course, but the integuments though hotter than on the outer surface of the limb, retain their natural colour and do not pit. Pressure over the situation of the femoral vein excites no pain, and the vein itself cannot be felt. ”
