“ René’s eldest surviving son by his marriage with Philippa, daughter of Adolphus of Egmont, duke of Gelderland, was Anthony, who succeeded his father as duke of Lorraine (d. 1544) , while the second, Claude, count and afterwards duke of Guise, received the French fiefs. The Guises, though naturalized in France, continued to interest themselves in the fortunes of Lorraine, and their enemies were always ready to designate them as foreigners. ”

“ Henry III. eventually placed himself at the head of the League, and resumed the war against the Huguenots; but on the conclusion of peace (September 1577) he seized the opportunity of disbanding the Catholic associations. The king’s jealousy of Guise increased with the duke’s popularity, but he did not venture on an open attack, nor did he dare to avenge the murder by Guise’s partisans of one of his personal favourites, Saint-Mégrin, who had been set on by the court to compromise the reputation of the duchess of Guise. ”

“ Francis of Lorraine, 2nd duke of Guise (1519–1563) , “le grand Guise,” was born at Bar on the 17th of February 1519. As count of Aumale he served in the French army, and was nearly killed at the siege of Boulogne in 1545 by a wound which brought him the name of “Balafré.” Aumale was made (1547) a peerage-duchy in his favour, and on the accession of Henry II. the young duke, who had paid assiduous court to Diane de Poitiers, shared the chief honours of the kingdom with the constable Anne de Montmorency. ”

“ Meanwhile the pope had veered round to a Spanish alliance, and Guise, seeing that no honour was to be gained in the campaign, wisely spared his troops, so that his army was almost intact when, in August, he was hastily summoned home to repel the Spanish army which had invaded France from the north, and had taken St Quentin. On reaching Paris in October Guise was made lieutenant-general of the kingdom, and proceeded to prepare for the siege of Calais. ”

“ He was an accomplice in the first attack on Coligny’s life, and when permission for the massacre of Saint Bartholomew had been extorted from Charles IX. he roused Paris against the Huguenots, and satisfied his personal vengeance by superintending the murder of Coligny. He was now the acknowledged chief of the Catholic party, and the power of his family was further increased by the marriage (1575) of Henry III. with Louise of Vaudémont, who belonged to the elder branch of the house of Lorraine. ”

“ He was extremely dissolute, but as an open-handed patron of art and learning, as the protector and friend of Erasmus, Marot and Rabelais he did something to counter-balance the general unpopularity of his calculating and avaricious brother. ”

“ Metz was invested by the duke of Alva in October with an army of 60,000 men, and the emperor joined his forces in November. An army of brigands commanded by Albert of Brandenburg had also to be reckoned with. Charles was obliged to raise the siege on the 2nd of January 1553, having lost, it is said, 30,000 men before the walls. Guise used his victory with rare moderation and humanity, providing medical care for the sick and wounded left behind in the besiegers’ camp. ”

“ Guise remained at the court of Blois after receiving repeated warnings that Henry meditated treason. On the 25th of December he was summoned to the king’s chamber during a sitting of the royal council, and was murdered by assassins carefully posted by Henry III. himself. The cardinal of Lorraine was murdered in prison on the next day. The history of the Guises thenceforward centres in the duke of Mayenne (q.v.) .
By his wife, Catherine of Cleves, the third duke had fourteen children: among them Charles, 4th duke of Guise (1571–1640) ”

“ The memoirs of Francis, duke of Guise, covering the years 1547 to 1563, were published by Michel and Poujoulat in series 1, vol. iv. of their Coll. de mémoires. Among contemporary memoirs see especially those of the prince of Condé, of Blaise de Monluc and of Gaspard de Saulx-Tavannes. See also La Vie de F. de Lorraine, duc de Guise (Paris, 1681) , by J. B. H. du Trousset de Valincourt; A. de Ruble, L’Assassinat de F. de Lorraine, duc de Guise (1897) , where there is a list of the MS. sources available for a history of the house; R. de Bouillé, Hist. des ducs de Guise (4 vols., 1849) ”

“ They now entrenched themselves with the king at Orleans, and the Bourbon princes, Anthony, king of Navarre, and his brother Condé, were summoned to court. The Guises convened a special commission to try Condé, who was condemned to death; but the affair was postponed by the chancellor, and the death of Francis II. in December saved Condé. Guise then made common cause with his old rival Montmorency and with the Marshal de Saint André against Catherine, the Bourbons and Coligny. ”