National Institute for Occupational Safety and Health

“ Sulfuric acid-treated glass fiber filters were used to collect aniline and o-toluidine, while nitrobenzene was collected on the silica gel sorbent [1] . Nitrobenzene collection on silica gel tubes was significantly reduced under conditions of high relative humidity [1] . Dermal badge samplers (cotton pouch with 1 g silica gel) and gauze wipes were developed to estimate exposures via splashes, spills, and passive collection of aerosol vapors. ”

“ Aniline is toxic, poisonous and a potential human carcinogen. o-Toluidine is toxic and a potential human carcinogen. Nitrobenzene is toxic and poisonous. Nitrobenzene has a synergistic effect on the toxicity of aniline and o-toluidine [5] . Ethanol is flammable and a dangerous fire risk. ”

“ The method was evaluated for the collection of aniline, o-toluidine, and nitrobenzene on gauze wipes, passive dermal samplers, and 37-mm glass fiber filter/silica gel sorbent tube sampling train. NIOSH Manual of Analytical Methods (NMAM) , Fourth Edition ANILINE, o-TOLUIDINE, AND NITROBENZENE: METHOD 2017, Issue 1, dated 15 January 1998 - Page 4 of 5
Desorption efficiency (DE) for aniline (recovered from acid-treated filters) was determined to be 1.00 at 10 × LOD [1] . Aniline storage stability at 0.12 mg was 64% after 7 days [1] ; however, at 0.2 to 0.7 mg recovery was 93.8% [2] . ”