U.S. Census Bureau

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U.S. Census Bureau Geographic Areas Reference Manual (1994)

At both the region and division level, the framework of areas provides complete coverage of the entire Nation. The purpose of this framework is to provide large units that are roughly similar in terms of historical development, population characteristics, economy, and the like. As a result, the regions and divisions serve not only to summarize data for the same groups of States over a long period of time, but also to provide a larger geographic framework for comparative statistical analysis.
Source: Wikisource

U.S. Census Bureau Geographic Areas Reference Manual (1994)

The homogeneity principle involves combining a group of people, housing units, or business establishments with similar characteristics into a single geographic area. The purpose can be either to provide summary statistics or to ensure the statistical validity of the data collected from only a sample of respondents; in both cases, each component entity should have, insofar as feasible, a similar population, economy, land use, and/or physical environment throughout its extent. Conversely, homogeneity means identifying, as separate entities, those adjacent areas that are different.
Source: Wikisource

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