National Institute for Occupational Safety and Health

“ Prepare calibration graph (peak area vs. μg epichlorohydrin) . Determine desorption efficiency (DE) at least once for each lot of charcoal used for sampling in EPICHLOROHYDRIN: METHOD 1010, Issue 2, dated 15 August 1994 - Page 3 of 4 a. b. c. d. e. 10. the calibration range (step 8) . Prepare three tubes at each of five levels plus three media blanks. Remove and discard back sorbent section of a media blank sampler. Inject a known amount of epichlorohydrin (or a solution of epichlorohydrin) directly onto front sorbent section with a microliter syringe. Cap the tube. Allow to stand overnight. ”

“ Sampler: glass tube, 7 cm long, 6-mm OD, 4-mm ID, flame-sealed ends with plastic caps, containing two sections of activated (600 C) coconut shell charcoal (front =100 mg; back = 50 mg) separated by a 2-mm urethane foam plug. A silylated glass wool plug precedes the front section and a 3-mm urethane foam plug follows the back section. Pressure drop across the tube at 1 L/min airflow must be less than 3.4 kPa. Tubes are commercially available. Personal sampling pump, 0.01 to 0.2 L/min, with flexible tubing. ”

“ Syringes, 10- and 100-μL. Volumetric flasks, 1- and 10-mL. Metal file. SPECIAL PRECAUTIONS: Carbon disulfide is toxic and extremely flammable (flash point = 30 °C) ; work with it only in a hood. Epichlorohydrin is a strong irritant and sensitizer and may cause kidney injury [4] .
SAMPLING:
Calibrate each personal sampling pump with a representative sampler in line. Break the ends of the sampler immediately before sampling. Attach sampler to personal sampling pump with flexible tubing. ”