National Institute for Occupational Safety and Health

“ If W b > W f/10, report breakthrough and possible sample loss. Calculate concentration, C, of 1-octanethiol in the air volume sampled, V (L) :
EVALUATION OF METHOD: Analytical precision was determined by analyzing spiked sampling media [1] . The average desorption efficiency was 0.94. The breakthrough volume was greater than 15 L for a concentration of 14.6 mg/m at 40 °C and 80% RH. Overall precision, bias and storage stability were determined by sampling and analyzing generated atmospheres. Generated concentrations were independently verified [1] . ”

“ The working range is 0.05 to 1 ppm (0.3 to 6 mg/m 3) for a 10-L air sample.
INTERFERENCES: Presence of other volatile compounds may interfere with collection of 1-octanethiol or reduce capacity of sorbent tube.
OTHER METHODS: None evaluated by NIOSH.
NIOSH Manual of Analytical Methods (NMAM) , Fourth Edition, 8/15/94 1-OCTANETHIOL: METHOD 2510, Issue 2, dated 15 August 1994 - Page 2 of 3 REAGENTS: 1. 2. 3.
4. 5. 6.
EQUIPMENT:
Acetone*. 1-Octanethiol, ≥97% purity.* Calibration stock solution, 0.843 μg/μL. Dissolve 10 μL 1-octanethiol in 10 mL acetone. Prepare fresh daily. ”

“ Typical pressure drop across tube is 2.4 kPa at 0.05 L/min flow. Similar commercially available tubes, e.g., SKC #226-35-03, are acceptable. 2. Personal sampling pump, 0.01 to 0.2 L/min, with flexible connecting tubing. 3. ”