Pfizer

“ Myron wrote. "These blue chips will grow with the economy. We'll add to them on dips and as money comes in. Waiting for good entry points on some growth companies." What was Pfizer? He'd ask Jennifer. On the other hand, he thought, maybe it would be best to keep quiet about this account—at least for now. He put the statement in his pocket and walked down to the Old Port.
"What's Pfizer?" he asked Myron.
"Pharmaceutical company. Solid. The long term outlook for the drug industry is good." Oliver inquired about the fund that was listed on the statement. "Right," Myron said. ”

“ And what that does is, these specialized syringes allow pharmacists and vaccinators to extract an extra dose of the Pfizer vial — so making more doses available, of course.It also prioritizes the Defense Production Act raw materials that are used to produce the vaccine, so reducing bottlenecks. And it enables manufacturers — us to empower and invoke, I guess, an action for manufacturers to make sure we have the materials we need to get the vaccines out the door and in the arms of Americans. ”

“ David Kessler’s leadership, and the active participation of both Johnson & Johnson and Pfizer. And this is truly — I’m sorry, Johnson & Johnson and Merck. This is truly a story where there are no bad guys; there’s only good — only good actors here. Everybody got together and found ways to bring forward the timeline so we can get Americans fully vaccinated and into a very different place, in a very different part of that pandemic. ”

“ Well, the FDA has not even approved Johnson & Johnson yet. We have ordered enough Moderna and Pfizer vaccines to vaccinate the entire public, so that’s where our focus is on. We’ll see as it moves through the process. ”

“ If people have appointments to get the Pfizer and Moderna vaccine, we want them to keep those appointments. We have great faith in the effectiveness of those vaccines, and they have very strong safety profiles. ”

“ Pfizer and Moderna’s vaccine supply will now increase to more than 20 million doses going out to states, tribes, territories, and pharmacies. That’s double the number going out every week before we came into office. This presents an opportunity for everyone to increase their vaccinations, even as that supply and supply of Johnson & Johnson vaccine ramp up even further. The country must quickly work through this additional supply. ”

“ We've been able to step it up very, very rapidly. I never thought we could have a vaccine as quickly as we did, but I freed it up. I freed up the FDA. Dr. Hahn has done a great job. And they're ready to approve something when they come in.
The other thing that's happening that's very different is — you look at a company like Pfizer, a great company — really, one of the great companies of the world. Johnson & Johnson. They're all great companies. They're doing a lot of testing at a very rapid rate that nobody has ever seen anything like it. ”

“ As you know, we’ve done a lot to help accelerate their production. And they’ve maintained a steady cadence of production. And both Moderna and Pfizer appear on track to meet their first-quarter targets.We’ve also been working closely with J&J. And we said right at the beginning that they started with an inventory of about 4 million doses, which we distributed immediately ”

“ What is important and what I want to cover today is that any progress is a result of the hard work of many — people and entities working together for the greater good: vaccine manufacturers, Pfizer and Moderna; distribution partners at McKesson, FedEx, and UPS; governors, mayors, county officials, and their health departments; the thousands of providers, pharmacies, and members of the military; FEMA; and other states and federal employees that had been part of this vaccination effort. ”

“ Given the fact that there is a greater demand than there is supply, should we be putting all of our effort into getting the first dose into people, with less emphasis on the second dose?
Now, the reason for that — I have explained in the past — because the science has shown in both of the vaccines that we have currently available, the Moderna and the Pfizer — the strong data indicates that a prime boost gives a maximum response of 94 to 95 percent efficacy. ”

“ As a company that claims to “innovate every day to make the world a healthier place,” these claims from your leadership charged with research and development are alarming. As the American people deserve to know, I request that you provide the following information:
1. What efforts is Pfizer currently, or planning to, engage in to mutate the SARS-CoV-2 virus? 2. Does Pfizer intend to continue mutating the SARS-CoV-2 virus through gain-of-function, or directed evolution research, with the purpose of creating new vaccines before the variant is present in the greater population? ”

“ And on the next slide is an example here of a Pfizer-BioNTech vaccine, namely looking at neutralizing antibody titers after the first and second dose.
If you look there at day 21, which is the time that you would be giving the second dose, the antibody titers that are there are good enough to suppress infection but to some extent — I mean, when you look at the data of the degree of efficacy that you do get after one dose. But take a look at what happens after the second dose. The degree of increase is at least tenfold in both of these age groups that was studied. ”

“ In fact, I had showed you in a previous press briefing what the issue was when you have a first dose of, let’s say, for example, Pfizer vaccine — very similar to the Moderna: you get a response that is protective. In this case, it would be about 52 percent. However, the second dose brings that level of antibodies quite high, which gives it redundancy to prevent the evolution, as well as to protect against viral variants. ”

“ The age range that is currently authorized for the SARS-CoV vaccination, as you well know, is 18 and older from Moderna, 16 for Pfizer, and 18 for J&J. There are vaccine safety and immunogenicity studies in adolescents and children that are either ongoing and/or planned.
For example, Pfizer-BioNTech’s study in persons aged 12 to 15 is fully enrolled, as is the teen COVE study from Moderna in individuals 12 to 17. ”

“ Fauci said, there’s been tens of millions of doses of Pfizer and Moderna administered over the last several months, and millions of people, both in the U.S. and around the world, have been safely vaccinated.I think it’s important that — you know, we have here the FDA, and the FDA is the gold standard for ensuring the safety and the effectiveness of the vaccines. And today’s action, I think, is clear evidence that they’re taking every step necessary to ensure the American people have clear and transparent information about the safety and effectiveness of these vaccines. ”

“ What happens if you get doubly vaccinated people with the Pfizer and Moderna, for example — members of family, people coming in — like, I use the example of a daughter coming in from out of town who is doubly vaccinated, and a husband and wife doubly vaccinated, and maybe a next-door neighbor who you know are doubly vaccinated. ”

“ This is more than enough supply to continue the current pace of vaccinations of 3 million shots per day, and meet the President’s goal of 200 million shots by his 100th day in office—and continue on to reach every adult who wants to be vaccinated. We are working now with our state and federal partners to get anyone scheduled for a J&J vaccine quickly rescheduled for a Pfizer or Moderna vaccine. ”

“ Well, you know, if you look at the history of — take a look at what has gone on with the Moderna and the Pfizer, where you have, you know, literally tens and tens and tens of millions that’s watched as carefully — there have been no red flags.When you have a red flag of something that is as serious as thrombotic thrombocytopenia — particularly when you have an individual, one of whom died — you take that seriously. ”

“ So, the bottom line is the vaccines — Moderna and Pfizer — that are now being administered are clearly safe and are saving lives, and every American should get vaccinated when it’s their turn.
MS. PSAKI: Jordan. Q Thanks. Jeff, is the — is J&J production going to continue during this pause? And secondly, is the Biden administration considering ordering more doses of Pfizer/Moderna given — just in case this problem with J&J becomes prolonged? ”

“ Q So he is giving some of these Pfizer vaccines to the Canadians? MS. PSAKI: Again, I think we are focused now on vaccinating the American people. But we made this contribution to COVAX. We are committed to working through that organizing mechanism. And all — you know, there are a range of options on the table for how the United States can contribute to expand our contribution to the global effort to fight COVID. Q What’s the threshold for donating surplus vaccines? How many Americans need to be vaccinated before the U.S. will do that? ”

“ And as we increase supply, we’re carrying out a clear plan to get shots into the arms of 300 million Americans or more. And I know people want confidence that it’s safe. Well, I just toured, and that’s — where it’s being made. It takes more time to do the check for safety than it does to actually make the vaccine. ”

“ On our tour, I met a few of your nearly 3,000 workers, Albert: experts managing ingredients that come in from different cities and states; experts handling 3D modeling and artificial intelligence to ensure that every dose is properly crafted; experts ensuring an environ- — a sterile environment so that each vial — each and every one — is safe and free of contaminants. ”

“ THE GIGANTIC MEDICAL AND VACCINE INTEREST SUPPORTING COMPULSORY VACCINATION A MENACE TO PUBLIC RIGHT AND SAFETY WHICH SHOULD BE CURBED The latest official reports show that there are now ninety-nine concerns licensed by the U. S. Government to manufacture vaccines and serums for both human and animal uses! These ninety-nine concerns have a capitalization of about fifty millions or more. One of the largest of these manufacturers, located in Detroit, has a capital of ten millions, while another large concern located in Philadelphia has a capital of two millions. ”

“ Their sale in interstate commerce is permitted under the license granted to the latter firm by the U. S. Treasury Department. However, no evidence of any kind was presented to the Council proving the therapeutic efficacy of the several mixed vaccines. As a mixture of two or more kinds of organisms is accepted for New and Non­official Remedies only if there is satisfactory evidence that its therapeutic use is rational, the Council declared the several vaccine mixtures ineligible for New and Non­official Remedies (Rule 10) .— (From Reports of Council on Pharmacy and Chemistry, 1919, p. 90.) ”

“ More than 90 percent of Americans live within five miles of a pharmacy. And I don’t know about you — my mother-in-law, my family calls me all the time, figuring out how they can call the CVS and find out when they can get their vaccine. This is a limited launch of the program, but supply will ultimately go up to 40,000 pharmacies nationwide. ”

“ But what the clear advice from our health and medical team is — and they’ve looked closely at all of the questions you’ve raised, all important ones — is that if you have access — for the American people: If you have — whatever vaccine you have access to, you should take that vaccine. ”

“ The circumstances attending this reintroduction of an original vaccinia, which I have recently detailed elsewhere, [5] strongly impressed me with the idea that the vaccine virus became "tempered" (so to speak) by passing through the human body, its original potency suffering diminution with the increase in the number of subjects through which it had been transmitted; while, at the same time, the proportion of subjects in whom the vaccination "took," which had been small with the original "vaccine," increased when it had (so to speak) become "humanized." ”

“ In other words, if the vaccinations are properly given, “never during a negative phase,” and as a result the patient’s tissues are stimulated to an increased production of the opsonins, phagocytosis is increased, the invading bacteria are disposed of, and the patient recovers from his infection. The proper handling of patients according to this method requires the greatest attention to details of technique for obtaining the opsonic index, preparing the vaccine, and the administration of the proper dose at the proper time. ”

“ At the end of twenty days’ injections they found they could obtain such a large quantity of anti-rabic substance in the serum of an animal, that even 1 part of serum to 25,000 of the body weight would protect an animal. This process differs from that of Pasteur in so far as that in place of promoting the formation of the antidote within the body of the patient, by a process of vaccination with progressively stronger and stronger virus, this part of the process is carried on in an animal, Babes using the dog and Centanni the sheep, the blood serum of which is injected. ”

“ You must recall that this vaccine trial was done on three continents — the United States, South America, and South Africa — with varying degrees of infection dynamics, as well as varying strains, variants, or lineages. That is the 66 percent. The 72 percent is the vaccine efficacy against moderate to severe critical infection in the United States.
I want to point out again a question we often get asked. In order to try — we always say: What vaccine is better than the other vaccine? ”

“ Obviously, our focus is on our own FDA approval process here and ensuring that we make as much of the vaccine available to the American public.And we just rejoined, as you know, the World Health Organization because we believe that the more people who are vaccinated around the world, the safer we all are. ”