Spermaceti

“ In thoughts of the visions of the night, I saw long rows of angels in paradise, each with his hands in a jar of spermaceti. ”

“ Sodio-chloride of gold, 10 gr.; lard, 4 dr. In scrofulous and syphilitic swellings, indurations, ulcers, &c.
Ointment of Spermace′ti. Syn. Emollient dressing, Simple ointment, White o.; Unguentum cetacei (B. P., Ph. L. & D.) , U. spermatis ceti, L. Prep. 1. (Ph. L.) Spermaceti, 5 oz.; white wax, 14 dr.; olive oil, 1 pint, or q. s.; melt them together by a gentle heat, and stir the mixture until cold.
2. (Ph. D.) White wax, 1⁄2 lb.; spermaceti, 1 lb.; prepared lard, 3 lbs.; as the last.
3. (B. P.) Spermaceti, 5; white wax, 2; almond oil, 20, or a sufficiency; stir constantly, until it cools. ”

“ In most cases which have been investigated the divisions by which the spermatids arise from the spermatocytes are two in number, so that each spermatocyte gives origin to four spermatids. Each spermatid becomes a functional spermatozoon or male gamete. The gametogeny of the male therefore closely resembles that of the female, differing from it only in the fact that all the four products of the progamete become functional gametes, whereas in the female only one, the ovum, becomes functional, the other three (polar bodies) being abortive. ”

“ The semen, made up as it is of mixed products of the testes and accessory sexual glands, is very often abnormal, as would be expected in view of the frequency with which changes occur in the glands contributing to its formation. The normal semen is remarkably adapted to its function of nourishment and stimulation of the spermatozoa, and their conveyance to the internal female genital organs. The spermatozoa are extremely sensitive to changes in their environment, with the result that any alteration of the physical or biochemical content of the seminal fluid may cause death of the sperms. ”

“ These defects in spermatogenesis are of course evidenced in the semen by the presence of immature, or abnormal types of sperms. With cessation of spermatogenesis or degeneration of the epithelium of the entire gland, no sperms are formed. Not infrequently one finds numerous tubules, or even the entire testis in which the germinal epithelium is intact, but there is little or no evidence of mitosis, as in some tubules of Bull 6. The cells are several layers deep as in the normal condition, but they are not dividing. ”

“ In the male the testis is a specialized portion of the wall of the genital coelom, and has a structure comparable to that of the ovary. The spermatozoa pass through an orifice from the cavity of the testis to the genital capsule, and thence to the spermiduct. The spermiduct is provided with a glandular pouch, and opens into a terminal reservoir known as Needham’s sac or the spermatophore sac. The function of this pouch is to form the spermatophore, which is an elastic tube formed of structureless secretion and invaginated into itself. ”

“ It is much easier to understand why abnormal spermatozoa occur so frequently, or changes take place in the semen with death or weakening of the germinal elements, if we realize or stop to consider the highly differential process of spermatogenesis, and the various structures which contribute to the formation of the semen. We must come to realize that each part of the genital tract is essential to the normal functioning of the whole, and that the genital tract and reproduction are in turn dependent upon the proper functioning of the entire body. ”

“ The human spermatozoon measures about one six-hundredth of an inch in length. It is composed of protoplasm, the substance of which all living creatures are composed. The spermatozoa are believed to be developed from a parent sperm-cell, by the process of segmentation or subdivision, which process is common to all cell-life. The numerous spermatozoa dwell in a gelatinous substance, which, mingling with the other fluidic secretions of the glands of the male, constitutes the male seminal fluid, sperm, or semen, which is ejaculated by the male during the process of copulation. ”

“ Seen under a microscope, a single drop of semen reveals a multitude of spermatozoa swimming about in the prostate-carrying medium. It is in this form that the vitalizing male element meets the female infertile ovum. This mass of live and moving germs is poured all around and about the region in which the ovum lies waiting to be fertilized, and every one of them seems to be "rushing about like mad" to find what it is sent to do, namely, to meet and fertilize the ovum. ”

“ There does not appear to be any true copulation. The male deposits small, white, oval spermatophores, which consist of small bundles of spermatozoa cemented together by some glutinous substance, indiscriminately on any part of the body of the female. Such spermatophores are found on the bodies of both males and females from July to January, but they appear to be most numerous in our autumn. It seems probable that the spermatozoa make their way from the adherent spermatophore through the body wall into the body, and so by traversing the tissues reach the ovary. ”

“ Abnormalities in morphology may be classified into immature types, and deformities or imperfect development of the head and tail. Defective spermatogenesis occurs so frequently that it is not surprising to find spermatozoa in various stages of development cast into the excretory ducts. The various stages passed through in the development, from spermatogonia to adult sperm, are numerous, and it therefore is to be expected that we should see in abnormal semen many different immature forms. ”

“ Now fertilisation does not necessarily occur whenever the male organ comes in contact with the female organ. Fertilisation occurs only when a male-cell (spermatazoon) unites with a female-cell (ovum) ; in other words, when the spermatazoa in the seminal fluid of a man meet and unite with the germ or ovum in the body of a woman. That is the beginning of the child. This union of the two cells need not take place during or immediately after sexual intercourse. It may occur many hours, or even two or three weeks, after connection, because the spermatazoa have motion of their own. ”

“ When ready to examine, place a small quantity upon a warmed slide and apply a cover. The spermatozoa are readily seen with a one-sixth objective (Fig. 53) . Normally, they are abundant and in active motion.
Detection of semen in stains upon clothing, etc., is [p. 284] often important. The finding of spermatozoa, after soaking the stain for an hour in normal salt solution or dilute alcohol and teasing in the same fluid, is absolute proof that the stain in question is semen, although it is not possible to distinguish human semen from that of the lower animals in this way. ”

“ It is incorrect to suppose, as has been held by some{121} theorists, that one testicle give rise to male spermatozoa and the other to female spermatozoa, for both male and female offspring have been produced from the same male parent after one testicle or the other has been removed. The same is true in cases in which either ovary has been removed from the mother; that is, male and female offspring are produced from mothers in whom either ovary has been removed. ”

“ If the period of sexual excitement extends over fifteen to thirty minutes, the whole duct system from the epididymis to the ampulla becomes gorged with the secreted testicular product. This [57] secretion consists of active motile spermatozoa, of spermatic granules and of mucus. The latter is secreted by the ducts of the epididymis and the vas deferens, the testicle itself furnishing only spermatozoa, spermatic granules and a small amount of liquid, just sufficient in quantity to float the spermatozoa out of the testes into the ducts. ”

“ Oligospermia, with normal motility and vitality, is not absolute sterility, but is of high importance because the percentage of destruction of spermatozoa during their passage through the genital canal of the female is so enormous that the possibility of impregnation by semen which starts out with a deficient number is always poor. ”

“ Many of the spermatozoa, weaker than the others, perish on the way, and only a few continue the journey up through the uterus to the tube. When near the little ovum, which remains passive, their movements become more and more rapid, they seem to be attracted to it as if by a magnet, and finally one spermatozoön—just one—the one that happens to be the strongest or the nearest, makes a mad rush at it with its head, perforates it, and is completely swallowed up by it. ”

“ Spermatocytes and spermatids are seen in the more severe types of defective spermatogenesis, and are relatively uncommon, while the more mature forms that result from the transformations of spermatid to adult cell are very often seen. ”

“ When we say that the testes form their external secretion under sexual excitement only, we simply mean that they liberate or release spermatozoa under sexual excitement. The spermatozoa must be looked upon as the fertilizing element of the semen, while the liquid portion of the semen probably contains that mysterious element which, absorbed into the body, produces virility and which, passed out with the spermatozoa, may have an important role to perform in the fertilizing function. ”

“ The most reasonable interpretation of the spermatia is that they are abortive male cells. They have never been found to cause infection, and they have not the characters of conidia; the large size of their nuclei, the reduction of their cytoplasm and the absence of reserve material and their thin cell wall all point to their being male gametes. Although in the forms without aecidia the two generations are not sharply marked off from one another, we may look up the generation with single nuclei in the cells as the gametophyte and that with conjugate nuclei as the sporophyte. ”

“ To the secretion is then added the product of the vesicles, which contributes markedly to its fluid content, nourishes the sperms, and supplies the ferment which induces clotting of the semen when ejaculated. This is very important because the clot formed in the vagina protects the delicate spermatozoa from the hostile acid vaginal secretion. The prostate likewise adds bulk and nourishing substances, besides stimulating the spermatozoa to fuller and more lasting motility. ”

“ In the case of man, the problem is, fortunately, a very simple one. We can easily obtain a specimen of the man's semen and determine, by means of the microscope, whether it contains spermatozoa or not. If it does contain a normal number of lively, rapidly moving spermatozoa, the man is fertile, regardless of whether he ever had epididymitis or not. If the semen contains no spermatozoa, or only a few deformed or lazily moving ones, then he is sterile. ”

“ In the love episode, at the time when contact is deepest and most intense, one sees, if one reasons biologically, that the time that would be chosen by nature for the injection of spermatozoa (of the millions of which only one is to be chosen by chance to be united to the single ovum ordinarily developed each month) is the time when the container which is destined to be the seat of the future life was either most open or most turned toward the source of the spermatozoa. ”

“ If it be assumed that the testicles can secrete substances upon the influence of which the development of the secondary sexual characters depends, it is obvious that these substances have nothing to do with the spermatozoa, inasmuch as the testicles exert the influence under consideration at an age at which the formation of spermatozoa has not yet begun. ”

“ Semen which contains no spermatozoa, or in which the spermatozoa are motionless, is absolutely devoid of fertilizing power; in the case of such semen, it makes no difference whatever that the external genitals of the man generating it are strongly formed, that his testicles are of normal size, and that erection and ejaculation take place promptly. Of very little value, though not absolutely sterile, is semen containing very few living spermatozoa, or, among very numerous motionless spermatozoa, containing a few only that are engaged in active movement. ”

“ Usually the two daughter nuclei are formed in an undivided cell. The resting-stage between the two divisions is only partial. The nucleolus appears and divides into two (figs. 33-36) , and the chromosomes change into the dyad form (fig. 36) , in which they come into the second maturation spindle (figs. 37, 38) . The equatorial plate again shows 26 chromosomes (fig. 39) . The formation of the spermatozoa is peculiar in that the original spermatocyte cell-body, as a rule, does not divide; but the four nuclei resulting from the two maturation divisions develop into sperm-heads in one cell. ”

“ Thus it can be seen that the seminal secretion a man loses, either during a wet dream or in sexual intercourse, is not a simple, but a composite fluid, consisting of secretions of the testicles, prostatic gland, seminal vesicles, and also numerous mucous glands of the urethral canal.
The most important element of the seminal fluid is the secretion produced by the testicles and containing spermatozoa. Spermatozoa, or human embryos, are microscopically small living cells, which resemble very much in appearance tadpoles. ”

“ From time to time, they back out of such a cove and seek another mooring place.
“This ‘stationary hunting’ motion is less universal than the other two. Many individual spermatozoa fail to attain it. It seems probable that only the most vigorous individuals ever reach this stair”. It has not been encountered in unmixed semen or in any artificial mediums. It has been observed only when the spermatozoon is in the secretions of the female genital tract. It is 21most frequent when the spermatozoon is in contact with a nest of epithelial cells.... ”