Sex cell

“ Some authorities think that "every cell in the body is an organ of internal secretion", [2] and that thus each influences all the others. The sex glands are especially important as endocrine organs; in fact the somatic cells are organized around the germ cells, as pointed out above. Hence the sex glands may be considered as the keys or central factors in the two chemical systems, the male and the female type. ”

“ And the germ-cell may devour any amount of egg-protoplasma without losing its original paternal energy. As a rule a child inherits as many qualities from its mother as from its father.
Determination of sex Sex is determined after conception has taken place. At an early stage of the embryo certain cells are set apart. These, later, form the sex glands. Modern research claims to have discovered the secret of absolutely determining sex in the human embryo, but even if these claims are valid they have not as yet met with any general application. ”

“ It has taught us by experiment that boys come from their mother’s right side, and girls from her left side, and in a healthy mother the rhythm of sex [Pg 11] is regular. The symbolism of the Fall might indeed apply to the history of the cell which at first contains its own force of reproduction, but in the case of a female ovum deliberately parts with some of its original power in order that it may be replaced by the vital power of a male. The male cell also rends itself apart, and becomes quite unfit for reproductive purposes until it can find another cell with which to join. ”

“ When the scale of animal life is reached where egg-cell and sperm-cell have their habitats in different individuals, the attraction between ovum and spermatozoön, which is based upon a kind of erotic chemotropismus, is transferred to the two hosts who harbor the two different sex-cells. Thus the erotic chemotropismus between two cells has now grown to sex-attraction between two animals. But even at this stage the attraction sometimes exists only between the sex-cells, namely when fertilization takes place outside of the mother’s body. The best example of outside fertilization are the fishes. ”

“ The controlling factor in sex determination has been narrowed down to three possibilities; it is inherited either from the single cell contributed by the father or from the single cell contributed by the mother, or it is determined by the effect these two cells have upon each other at the moment when they unite. In most animal species the weight of authority distinctly favors placing the whole responsibility upon the male cell. ”

“ In man, two X-chromosomes have been discovered, half the sperm containing 12, and the other half containing only 10 chromosomes. The number of chromosomes in human cells consequently is 22 in the male and 24 in the female.
The X-chromosome is the bearer of sex destiny. There still remains the work to be done on the actual control of sex by man, apart from its natural determination. For the time being, let the feminists glory in the fact that they have two more chromosomes to each cell than their opponents. Certainly there can be no talk here of a natural inferiority of women. ”

“ The search for means of influencing the sex of the offspring through the mother is not of necessity doomed to failure. No results of a really positive kind have been obtained hitherto, and some of the facts point so clearly to sex-determination by the male germ-cell alone in man and other animals that many investigators have concluded that the quest is hopeless ”

“ Most cells can do no more than produce units like themselves. The bodies of women contain, however, a type of cell which possesses a far more wonderful power. Provided the requisite conditions for such development are met, these cells are capable of developing into human beings. Each of these remarkable units is called an Ovum, or egg-cell, and represents one variety of the germinal cells. But the other variety, represented by the Spermatozoon and developed only in the male sex, is also required for the production of a human being.
Every ovum originates in the ovaries. ”

“ It is a common belief that the original purpose of sex is to ensure reproduction, whereas fundamentally it is not necessary to propagation at all. It is perfectly true, of course, that [36] in the majority of animals, and also in many plants, an individual life begins in the union of two minute elements, the mother egg-cell and the sperm father-cell. But this is not the earliest stage, and below these higher forms we find a great world of life reproducing without this sex-process by simple separation and growth. ”

“ In most animals it is definitely known that the sex of the offspring has been fixed when the male cell enters the female cell, in other words, at the instant the ovum is fertilized. Excellent reasons exist for believing that human beings conform to this rule, and that the sex of the child is unalterably determined at the moment conception occurs. Consequently, any attempt to influence it after that event must prove futile. ”

“ The internal secretions of the genital glands must be regarded as completing the sexuality of the individual. Every cell must be considered as possessing an original sexuality, to which the influence of the internal secretion in sufficient quantity is the final determining condition under the influence of which the cell acquires its final determinate character as male or female.
The genital glands are the organs in which the sex of the individual is most obvious, and in the component cells of which it is most conspicuously visible. ”

“ As a result of these long inductions and deductions we may rest assured that all the cells possess a definite primary sexual determinant which must not be assumed to be alike or nearly alike throughout the same body. Every cell, every cell-complex, and every organ have their distinctive indices on the scale between thelyplasm and arrhenoplasm. For the exact definition of the sex, an estimation of the indices over the whole body would be necessary. ”

“ The present belief regarding the causation of sex is that although there is but one kind of ovum, there are two kinds of spermatozoa, one capable of producing a male and the other a female child, but the sex-determining form of the male cell that fertilizes any one ovum is a matter of the merest chance. Statistics show that more male than female babies are born, the usual proportion being about 105 boys to 100 girls among those who are carried to “term” or the end of pregnancy. ”

“ Still less can such confessedly morbid predominance be considered as a peculiar liability of the female sex in this race. A singular tendency exists in many quarters, and is strongly manifested in Dr. Clarke's book, to assume that considerations pertaining to sex and to the functions of reproduction exercise such an enormous influence upon one sex, and none at all upon the other. Since the discovery in 1827 of the ovule or female reproductive cell, there can be no question of the complete physiological equivalence and analogy between the essential organs of reproduction in the two sexes. ”

“ But even at this point it becomes evident that the true office of sex was not the first need of securing reproduction—that had been done already—rather it was the improving and perfecting of the single-cell process by introducing variation through the commingling of the ancestral hereditary elements of two parents, and, by means of such variations, the production of new and higher forms of life—in fact, progress by the mighty dynamic of sex. ”

“ At present empirical knowledge does not enable us to say wherein the masculinity or the femininity of a cell really lies, or to define the histological, molecular or chemical differences which distinguish every cell of a male from every cell of a female. Without anticipating any discovery of the future (it is plain already, however, that the specific phenomena of living matter are not going to be referred to chemistry and physics) , it may be taken for granted that individual cells possess sexuality in different degrees quite apart from the sexuality of the whole body. ”

“ This is by no means to say that conditions affecting the mother—as, for74 instance, the semi-starvation of a prolonged siege—may not affect the construction of the germ-cells which she houses, and which are constantly being formed within her from the mother germ-cells, as they are called. But any given final germ-cell, such as will combine with another from an individual of the opposite sex to form a new being, is already determined, once for all, to be of one sex or the other. ”

“ The meaning of the ovaries as sources of the egg-cells and of the uterus as the place for development of the fertilized egg-cell should be explained in a serious way that will help boys get some fundamental ideas as to what motherhood means Boys, moreover, should be informed concerning the existence of the periodic disturbance in the other sex, for unless they know they are sure at times to misunderstand their sisters and other girls. ”

“ The Semites founded their opinion of women on fabulous legends and false science. They assert that man gives the spirit and woman the matter to the child. Embryology has now taught us that the parents make exactly equal contributions of chromatin, or the active element, to the original cell from which a child develops. It has taught us that, originally, cells are capable of self-reproduction; that sex is not always a vital necessity, but often a device for securing variety. ”

“ The proof that every single organ, and further, that every single cell possesses a sexuality lying somewhere between arrhenoplasm and thelyplasm, and further, that every cell received an original sexual endowment definite in kind and degree, is to be found in the fact that even in the same organism the different cells do not always possess their sexuality identical in kind and degree. In fact each cell of a body neither contains the same proportion of M and W nor is at the same approximation to arrhenoplasm or thelyplasm ”

“ Here—since it is obviously impossible for all the cells of one individual to fuse with all the cells of another—certain special cells are set apart in each organism for the purpose of union or conjugation; and it seems quite natural that in the course of time the differentiation spoken of above, into male and female, should set in—each individual tending to become decisively either masculine or feminine—both in the sex-cells or sex-apparatus, and (though in a less marked degree) in the general ‘body’ and structure. ”

“ Then as each somatic cell is descended without segregation from the fertilised ovum, we may suppose that the presence of the sex-chromosomes in the somatic cells themselves in some way determines whether male or female characters shall develop, without the aid of any hormones from the gonads. This theory would be quite compatible with the belief that adaptive somatic sex-characters may be due to external stimulation, for supposing that the hypertrophy or modification is conveyed to the determinants in the gametocytes, and was confined to one sex, e.g. ”

“ The development of reproductive cells in special glandular apparatus at the period of puberty, is evidently not peculiar to one sex, but is a physiological fact necessarily common to both. The peculiarity in the female consists in the greater degree of periodicity in the complete development of such cells, in the periodical congestions of a secondary organ, the uterus, and in the loss of blood effected by these. ”

“ Even in many complex multicellular organisms the liberation of the sex-elements continues very passive; and although the differentiation of the sexual-cells is already complete in plants and animals comparatively low in the scale, it at first makes little difference in the development of the other parts of the individual. Among many lower animals, and most plants, each individual develops within itself both kinds of cells—that is, female and male. This union of the two sex functions in one organism is known as hermaphroditism. ”

“ If the activity of the generative apparatus of the female should be increased by any circumstance, in the case of the animals the ripening of the ovum would be accelerated. The consequence would be an earlier detachment or emptying out of the ova from the ovary. In consequence, the generative operations in the animal are of a more complex nature than in plants, a fact which is of great significance for the determination of sex. ”

“ It is probable, therefore, that if it will ever be possible to predict or determine artificially the sex of a particular child, the means will have to be sought in some method of influencing the output of germ-cells in such a way that one kind is produced rather than the other. It is in this way that Heape and others interpret the results of their investigations; they find that certain conditions affect the sex-ratio of cells, and they explain the result by assuming that under some circumstances male-determining ova are produced in excess, and under other circumstances, female-determining. ”

“ The chances are half and half that the new individual thus begun will be of a given sex, for the following reason: There is a structural difference, supposed to be fundamentally chemical, between the cells of a female body and those of a male. ”

“ When the general principles arrived at are borne in mind, it must be confessed that the prospects of our ever attaining this power of control or even of prediction are not very hopeful, but the possibility of it cannot be yet regarded as entirely excluded. The general conclusions arrived at are that sex is determined by a physiological condition of the embryonic cells, that this condition is induced, at least in the absence of disturbing causes, by the presence of a particular sex-chromosome. ”