William Osler

“ He was, in the first place, a naturalist to whom pathological processes were only a small part of a stupendous whole, governed by law, which, however, could never be understood until the facts had been accumulated, tabulated and systematized. By his example, by his prodigious industry, and by his suggestive experiments he led men again into the old paths of Aristotle, Galen and Harvey. He made all thinking physicians naturalists, and he lent a dignity to the study of organic life, and re-established a close union between medicine and the natural sciences. ”

“ Morgagni's life had as much influence as his work. In close correspondence with the leading men of the day, with the young and rising teachers and workers, his methods must have been a great inspiration; and he came just at the right time. The profession was literally ravaged by theories, schools and systems—iatromechanics, iatrochemistry, humoralism, the animism of Stahl, the vitalistic doctrines of Van Helmont and his followers—and into this metaphysical confusion Morgagni came like an old Greek with his clear observation, sensible thinking and ripe scholarship. ”

“ To the age of the hearer, in which men had heard and heard only, had succeeded the age of the eye in which men had seen and had been content only to see. But at last came the age of the hand—the thinking, devising, planning hand, the hand as an instrument of the mind, now re-introduced into the world in a modest little monograph from which we may date the beginning of experimental medicine. ”

“ THE true and lawful goal of the sciences is none other than this: that human life be endowed with new discoveries and powers. (Francis Bacon, Novum Organum, Aphorisms, LXXXI, Spedding's translation.)
A GOLDEN thread has run throughout the history of the world, consecutive and continuous, the work of the best men in successive ages. From point to point it still runs, and when near you feel it as the clear and bright and searchingly irresistible light which Truth throws forth when great minds conceive it. ”

“ Insatiate in experiment, intellectually as greedy as Aristotle, painter, poet, sculptor, engineer, architect, mathematician, chemist, botanist, aeronaut, musician and withal a dreamer and mystic, full accomplishment in any one department was not for him! A passionate desire for a mastery of nature's secrets made him a fierce thing, replete with too much rage! But for us a record remains—Leonardo was the first of modern anatomists, and fifty years later, into the breach he made, Vesalius entered. ”

“ FOR the mind depends so much on the temperament and disposition of the bodily organs that, if it is possible to find a means of rendering men wiser and cleverer than they have hitherto been, I believe that it is in medicine that it must be sought. It is true that the medicine which is now in vogue contains little of which the utility is remarkable; but, without having any intention of decrying it, I am sure that there is no one, even among those who make its study a profession, who does not confess that all that men know is almost nothing in comparison with what remains to be known ”

“ At a period when authority was paramount, and men blindly followed old leaders, when to stray from the beaten track in any field of knowledge was a damnable heresy, he stood out boldly for independent study and the right of private judgment. After election to the chair at Basel he at once introduced a startling novelty by lecturing in German. He had caught the new spirit and was ready to burst all bonds both in medicine and in theology. He must have startled the old teachers and practitioners by his novel methods. ”

“ What would have been its fate if the mind of Europe had been ready for Roger Bacon's ferment, and if men had turned to the profitable studies of physics, astronomy and chemistry instead of wasting centuries over the scholastic philosophy and the subtleties of Duns Scotus, Abelard and Thomas Aquinas? Who can say? Make no mistake about the quality of these men—giants in intellect, who have had their place in the evolution of the race ”

“ Into the content of mediaeval thought only a mystic can enter with full sympathy. It was a needful change in the evolution of the race. Christianity brought new ideals and new motives into the lives of men. The world's desire was changed, a desire for the Kingdom of Heaven, in the search for which the lust of the flesh, the lust of the eye and the pride of life were as dross. A master-motive swayed the minds of sinful men and a zeal to save other souls occupied the moments not devoted to the perfection of their own. ”

“ He who went about doing good was a physician of the body as well as of the soul, and could the rich promises of the Gospel have been fulfilled, there would have been no need of a new dispensation of science. It may be because the children of this world have never been able to accept its hard sayings—the insistence upon poverty, upon humility, upon peace that Christianity has lost touch no less with the practice than with the principles of its Founder. Yet, all through the centuries, the Church has never wholly abandoned the claim to apostolic healing ”

“ Nothing illustrates more clearly the interdependence of the sciences than the reciprocal impulse given to new researches in pathology and entomology by the discovery of the part played by insects in the transmission of disease. The flea, the louse, the bedbug, the house fly, the mosquito, the tick, have all within a few years taken their places as important transmitters of disease. The fly population may be taken as the sanitary index of a place. The discovery, too, that insects are porters of disease has led to a great extension of our knowledge of their life history. ”

“ If, in the memorable phrase of the Greek philosopher, Prodicus, "That which benefits human life is God," we may see in this new gospel a link betwixt us and the crowning race of those who eye to eye shall look on knowledge, and in whose hand nature shall be an open book—an approach to the glorious day of which Shelley sings so gloriously:
Happiness And Science dawn though late upon the earth; Peace cheers the mind, health renovates the frame ”

“ But the high-water mark of professional morality is reached in the famous Hippocratic oath, which Gomperz calls "a monument of the highest rank in the history of civilization." It is of small matter whether this is of Hippocratic date or not, or whether it has in it Egyptian or Indian elements: its importance lies in the accuracy with which it represents the Greek spirit. For twenty-five centuries it has been the "credo" of the profession, and in many universities it is still the formula with which men are admitted to the doctorate. ”

“ Even before the full demonstration of the germ theory, they had grasped the conception that the battle had to be fought against a living contagion which found in poverty, filth and wretched homes the conditions for its existence. One terrible disease was practically wiped out in twenty-five years of hard work. It is difficult to realize that within the memory of men now living, typhus fever was one of the great scourges of our large cities, and broke out in terrible epidemics—the most fatal of all to the medical profession. ”

“ Of all the organs inspected in a sacrificial animal the liver, from its size, position and richness in blood, impressed the early observers as the most important of the body. Probably on account of the richness in blood it came to be regarded as the seat of life—indeed, the seat of the soul. From this important position the liver was not dislodged for many centuries, and in the Galenic physiology it shared with the heart and the brain in the triple control of the natural, animal and vital spirits. Many expressions in literature indicate how persistent was this belief. ”

“ But we have gradually reached a stage in which knowledge is translated into action, made helpful for suffering humanity, just as the great discoveries in physics and chemistry have been made useful in the advance of civilization. We have traced medicine through a series of upward steps—a primitive stage, in which it emerged from magic and religion into an empirical art, as seen among the Egyptians and Babylonians; a stage in which the natural character of disease was recognized and the importance of its study as a phenomenon of nature was announced ”

“ In a letter to one of the editors, Osler described these lectures as "an aeroplane flight over the progress of medicine through the ages." They are, in effect, a sweeping panoramic survey of the whole vast field, covering wide areas at a rapid pace, yet with an extraordinary variety of detail. The slow, painful character of the evolution of medicine from the fearsome, superstitious mental complex of primitive man, with his amulets, healing gods and disease demons, to the ideal of a clear-eyed rationalism is traced with faith and a serene sense of continuity. ”

“ WHEN the thoughtful historian gets far enough away from the nineteenth century to see it as a whole, no single feature will stand out with greater distinctness than the fulfilment of the prophecy of Descartes that we could be freed from an infinity of maladies both of body and mind if we had sufficient knowledge of their causes and of all the remedies with which nature has provided us. Sanitation takes its place among the great modern revolutions—political, social and intellectual. ”

“ In the Hippocratic writings is summed up the experience of Greece to the Golden Age of Pericles. Out of philosophy, out of abstract speculation, had come a way of looking at nature for which the physicians were mainly responsible, and which has changed forever men's views on disease. Medicine broke its leading strings to religion and philosophy—a tottering, though lusty, child whose fortunes we are to follow in these lectures. ”

“ The brotherhood of man, the care of the body, the gospel of practical virtues formed the essence of the teaching of the Founder—in these the Kingdom of Heaven was to be sought; in these lay salvation. But the world was very evil, all thought that the times were waxing late, and into men's minds entered as never before a conviction of the importance of the four last things—death, judgment, heaven and hell. ”

“ Cholera kills its thousands, plague, in its bad years, its hundreds of thousands, yellow fever, hookworm disease, pneumonia, tuberculosis, are all terribly destructive, some only in the tropics, others in more temperate regions: but malaria is today, as it ever was, a disease to which the word pandemic is specially applicable. In this country and in Europe, its ravages have lessened enormously during the past century, but in the tropics it is everywhere and always present, the greatest single foe of the white man, and at times and places it assumes the proportions of a terrible epidemic. ”

“ I believe it was Hegel who said that progress is a series of negations—the denial today of what was accepted yesterday, the contradiction by each generation of some part at least of the philosophy of the last; but all is not lost, the germ plasm remains, a nucleus of truth to be fertilized by men often ignorant even of the body from which it has come. Knowledge evolves, but in such a way that its possessors are never in sure possession. "It is because science is sure of nothing that it is always advancing" (Duclaux) . ”

“ History is the biography of the mind of man, and its educational value is in direct proportion to the completeness of our study of the individuals through whom this mind has been manifested. I have tried to take you back to the beginnings of science, and to trace its gradual development, which is conditioned by three laws. In the first place, like a living organism, truth grows, and its gradual evolution may be traced from the tiny germ to the mature product. Never springing, Minerva-like, to full stature at once, truth may suffer all the hazards incident to generation and gestation. ”

“ Many scientific discoveries have afforded brilliant illustrations of method in research, but in the work of these men one is at a loss to know which to admire more—the remarkable accuracy and precision of the experiments, or the heroism of the men—officers and rank and file of the United States Army; they knew all the time that they were playing with death, and some of them had to pay the penalty! The demonstration was successful—beyond peradventure—that yellow fever could be transmitted by mosquitoes, and equally the negative proposition—that it could not be transmitted by fomites. ”

“ The purpose of this course of lectures is to sketch the main features of the growth of these two dominant ideas, to show how they have influenced man at the different periods of his evolution, how the lamp of reason, so early lighted in his soul, burning now bright, now dim, has never, even in his darkest period, been wholly extinguished, but retrimmed and refurnished by his indomitable energies, now shines more and more towards the perfect day. ”

“ The glory of this zeal for the enrichment of this present life was revealed to the Greeks as to no other people, but in respect to care for the body of the common man, we have only seen its fulfilment in our own day, as a direct result of the methods of research initiated by them. Everywhere throughout the Hippocratic writings we find this attitude towards life, which has never been better expressed than in the fine phrase, "Where there is love of humanity there will be love of the profession." This is well brought out in the qualifications laid down by Hippocrates for the study of medicine. ”

“ Thou art my leader, and the footprints shine, Wherein I plant my own.... The world was shine to read, and having read, Before thy children's eyes thou didst outspread The fruitful page of knowledge, all the wealth Of wisdom, all her plenty for their bread. ”

“ The central figure was a man not yet in the prime of life, and justly full of its pride, as you may see from his portrait. Like Aristotle and Hippocrates cradled and nurtured in an AEsculapian family, Vesalius was from his childhood a student of nature, and was now a wandering scholar, far from his Belgian home. But in Italy he had found what neither Louvain nor Paris could give, freedom in his studies and golden opportunities for research in anatomy. ”