The Commerce Clause, enshrined in Article I, Section 8, Clause 3 of the U.S. Constitution, confers Congress the power to regulate trade with foreign nations, between states, and with Indian Tribes. This authority has been interpreted broadly, from Marshall Court decisions concerning navigable waters to contemporary discussions about the extent of economic activities.
Legal experts and judges, including Byron White and Antonin Scalia, have examined its limits, highlighting both federal oversight of the economy and constraints on state involvement. The Clause's developing legal interpretation illustrates the balance between national cohesion and state independence, influencing federal regulatory authority since the 19th century.