Chemical theory

“ In the meanwhile, the primitive atomic theory, which has served as the scaffolding for the edifice of modern physics and chemistry, has been quietly dismissed. I cannot discover that any contemporary physicist or chemist believes in the real indivisibility of atoms, or in an interatomic matterless vacuum. 'Atoms' appear to be used as mere names for physico-chemical units which have not yet been subdivided, and 'molecules' for physico-chemical units which are aggregates of the former. ”

“ After becoming acquainted with the constituent elements of all the substances within our reach and the mutual relations of these elements, the remarkable transmutations to which the bodies are subject under the influence of the vital powers of plants and animals, became the principal object of chemical investigations, and the highest point of interest. A new science, inexhaustible as life itself, is here presented us, standing upon the sound and solid foundation of a well established inorganic chemistry. ”

“ The fundamental task of inorganic chemistry is still connected with the classification of elements and compounds. The investigation of the classification of carbon compounds forms the field of organic chemistry; while general or physical chemistry deals with the laws of reaction, and the influence of various forms of energy in furthering or hindering chemical change. ”

“ May we not, therefore, conclude that the chemical action exhibited in a burning body is a development of some latent force, with which we are unacquainted, produced by the absorption of light;—that a repulsive action at first takes place, by which the hydrogen and carbon are separated from each other;—and that in the nascent state they are seized by the oxygen, and again compelled, though in the new forms of water and carbonic acid, to resume their chains of combining affinity? ”

“ Of which is the sugar experiment an example? Metathesis is an exchange of atoms in two different compounds; it gives rise to still other compounds.
A chemical change may add something to a substance, or subtract something from it, or it may both subtract and add, making a new substance with entirely different properties. Sulphur and carbon are two stable solids. The chemical union of the two forms a volatile liquid. A substance may be at one time a solid, at another a liquid, at another a gas, and yet not undergo any chemical change, because in each case the chemical composition is identical. ”

“ The peculiar manner in which hydrogen gas appears to dissolve solid substances,—as iron, potassium, sodium, sulphur, phosphorus, selenium, and arsenic, may be explained by regarding the results as a manifestation of the powers of chemical affinity over the forms of bodies. In like manner, the solution of salt in water, or the mixture of alcohol in that fluid, may be viewed as chemical phenomena, although usually considered as simple cases of solution or mixture: alterations of temperature and other physical changes taking place in either. ”

“ When this element, nitrogen, is combined with the wonderful variety of compounds formed by carbon, we have not only a great many intimately related yet distinct [100] substances, but compounds which readily change from one form to another. These are the distinctive qualities or conditions necessary, from a chemical standpoint, to make the processes of life possible. Protoplasm, which is the basis of all life, is formed by an intimate mixture of a number of complex chemical compounds, the chief elements of which are carbon, hydrogen, oxygen, and nitrogen. ”

“ The subject of Organic Chemistry is that to which, at the present day, the eyes of all thinking members of the profession are directed, and upon which their hope of progress mainly depends,—the relations of chemical action to the functions of organized matter, the application of chemistry to physiology and pathology, are to be treated of as fully as present knowledge extends. ”

“ So the synthesis of a single organic compound sufficed at a blow to break down the chemical barrier which the imagination of the fathers of the science had erected between animate and inanimate nature. Thenceforth the philosophical chemist would regard the plant and animal organisms as chemical laboratories in which conditions are peculiarly favorable for building up complex compounds of a few familiar elements, under the operation of universal chemical laws. ”

“ The mysteries of organic chemistry are great, and the differences between its processes or reactions as they are carried out in the organism and in the laboratory are many421. The actions, catalytic and other, which go on in the living cell are of extraordinary complexity. But the contention that they are different in kind from what we term ordinary chemical operations, or that in the production of single asymmetric compounds there is actually to be witnessed, as Pasteur maintained, a “prerogative of life,” would seem to be no longer safely tenable. ”

“ But as soon as the solution is rendered stronger, or the solvent and the dissolved body are endowed with a mutual chemical affinity, chemical reactions set in. Part of the molecules of the dissolved body dissociate, and the atoms of which they were composed, on being set free, combine with the atoms of the solvent. Chemical forces, much more energetic than the physical forces, enter into play, and most complicated chemical reactions—the intensity of which may be judged of from the changes of temperature—begin. ”

“ The study of the structure of molecules naturally leads to the study of their stability, and of the conditions which determine chemical changes, and thus opens the recently explored field of thermo-chemistry. To be able to predict the order and results of possible conditions of association of materials, or of chemical changes under all circumstances, is now the highest aim of our science, and we have already made very considerable progress toward this end. ”

“ Numerous phenomena of even a more striking character than those selected, are exhibited in every department of chemistry; but within the limits of this essay it is impracticable to speak of any beyond those which directly explain natural phenomena.
The chemical elements, which actually exist in nature as simple bodies, are probably but few. Most of the gases are in all probability compounds of some ethereal ultimate principles; and with the advance of science we may fairly hope to discover the means of reducing some of them to a yet more simple state. ”

“ Organic compounds, on which our life and living depend, consist chiefly of four elements: carbon, hydrogen, oxygen and nitrogen. These compounds are sometimes hard to analyze, but when once the chemist has ascertained their constitution he can usually make them out of their elements—if he wants to. He will not want to do it as a business unless it pays and it will not pay unless the manufacturing process is cheaper than the natural process. ”

“ This explains why salts are usually inactive and neutral in character, while acids and bases are active agents. Thus we see why the most positive or the most negative elements in general have the strongest affinities, while those intermediate in the list are inactive, and have weak affinities; why alloys of the metals are weak compounds; why a neutral substance, like water, has such a weak affinity for the salts which it holds in solution; and why an aqueous solution is regarded as a mechanical mixture rather than a chemical compound. ”

“ The idea of chemical composition is an idea of transformation, but of a transformation which is incomplete; since we consider the oxygen and hydrogen to be present in the water as oxygen and hydrogen, and capable of being discovered in it if our senses were sufficiently keen: a supposition (for it is no more) grounded solely on the fact that the weight of the water is the sum of the separate weights of the two ingredients. ”

“ Although it may appear that some cases of chemical combination are due to these powers,—as, for instance, when the union of oxalic acid or sulphuric acid with lime produces an insoluble salt,—we cannot thus explain the constant proportions in which the metals, sulphur, oxygen, and similar bodies, unite. It is quite certain there is a power or principle, which we [Pg 286] have not yet reached, upon which are dependent all the phenomena which we now embrace under the term chemical affinity. ”

“ We don't all want to be analytical chemists: but what we do all want is to know as much about oxygen and carbon as will enable us to understand the commonest phenomena of combustion, of chemical combination, of animal or vegetable life. ”

“ The numerous practical applications which the teacher of organic chemistry has at his command will always serve to make this subject one of the deepest interest, if not the most fascinating portion of the entire subject of chemistry. No student should leave the course in organic chemistry without feeling the beautiful unity and logical relationship which obtains in the case of the compounds of carbon, the experimental study of which has cast so much light upon the chemical processes in living plants and animals, processes upon which life itself depends. ”

“ Thus we learn that chalk is a body consisting of two compound molecules,—carbonic acid, which is formed by the combination of an atom of carbon with two atoms of oxygen,—and lime, which results from the union of an atom of calcium with one of oxygen.
The condition requisite to the production of chemical action between bodies is that they should be dissimilar. Two elementary atoms are placed within the spheres of each other’s influences, and a compound molecule results. Oxygen and hydrogen form water; oxygen and carbon give rise to carbonic acid; nitrogen and hydrogen unite to form ammonia ”

“ The facility with which chemical inquiries are carried on, and the simplicity of the apparatus, offer additional reasons, to those I have already given, for the pursuit of this science. It is not injurious to the health; the modern chemist is not like the ancient one, who passed the greater part of his time exposed to p. 174the heat and smoke of a furnace and the unwholesome vapours of acids and alkalies and other menstrua, of which, for a single experiment, he consumed several pounds. ”

“ It must not be understood that this force, which I finally came to control, annihilated matter; it merely annihilated form. Nor, as I soon discovered, had it any effect on inorganic structure; but to all organic form it was absolutely fatal. This partiality puzzled me at first, though had I stopped to think deeper I would have seen through it. Since the number of atoms in organic molecules is far greater than in the most complex mineral molecules, organic compounds are characterized by their instability and the ease with which they are split up by physical forces and chemical reagents. ”

“ When oxygen combines with a single element, what is the compound called? We have found that O makes up a certain portion of the air; later, we shall see how large the proportion is. Its tendency to combine with almost everything is a reason for the decay, rust, and oxidation of so many substances, and for conflagrations, great and small. New compounds are thusformed, of which O constitutes one factor. Water, H2O, is only a chemical union of O and H. Iron rust, Fe2O3 and H2O, is composed of O, Fe, and water. The burning of wood or of coal gives rise to carbon dioxide, CO2, and water. ”

“ Chemical affinity depends entirely upon the energy with which particles of different kinds attract each other. Oxygen and hydrogen are particles of different kinds, and it is their attraction to each other which makes them chemically combine and produce water. ”

“ To take a simple example:—oxygen and hydrogen are two gases which may be mixed in all proportions at ordinary temperatures, and it is easy to show that the properties of the products are simply those of mixtures of the two free gases. If, however, an electric spark be passed through the mixtures, powerful chemical union ensues, with its concomitants, great evolution of heat and consequent rise of temperature, and a compound, water, is formed which presents physical and chemical properties entirely different from those of its constituents. ”

“ The student will thus be brought to the chemical conception of the molecule as the smallest mass of any substance in which the qualities inhere, and he will come to regard a chemical process as always taking place between molecules.
Thus far nothing has been said about the composition of matter. A chemical process has been defined simply as certain factors yielding certain products, but nothing has been determined about the relations of these several substances except in so far as they are defined by the three laws illustrated above. ”

“ Moreover, the important fact must be fully recognized that in living beings we have to do with no new elementary forms of matter. Precisely the same atoms which build up the inorganic fabric, compose the organic. In the early days of chemistry, indeed, it was supposed that the complicated molecules which life produced were beyond the reach of simple chemical law. But as more and more complex molecules have been, one after another, produced, chemistry has become re-assured, and now doubts not her ability to produce them all. ”

“ It brings home to me what an unstable chemical compound man is. Here are the stage accessories as good as ever, while the players have all split up into hydrogen and oxygen and nitrogen and carbon, with traces of iron and silica and phosphorus. ”

“ Compare CO and CO2. (3) In the arrangement of atoms, i.e. the molecular structure. Ethyl alcohol and methyl ether have the same number of the same elements, C2H6O, but their molecular structure is not the same, and hence their properties differ.
Qualitative analysis shows what elements enter into a compound; quantitative analysis shows the proportion of these elements; structural analysis exhibits molecular structure, and is the branch to which organic chemists are now giving particular attention. `
A specialist often works for years to synthesize a series of compounds in the laboratory. ”