O. A. Johannsen, Handbook of Medical Entomology
“ The effect of the bite varies greatly with different species and depends upon the susceptibility of the individual bitten. Some persons are driven almost frantic by the attacks of the pests when their companions seem almost unconscious of any inconvenience. Usually, irritation and some degree of inflammation appear shortly following the bite. Not infrequently a hardened wheal or even a nodule forms, and sometimes scratching leads to secondary infection and serious results.The source of the poison is usually supposed to be the salivary glands of the insect. ”
