Mucus

“ Of the effusion of mucus and lymph from natural causes.—The abundant secretion of tough mucus in the stomach is a sign of that organ having been irritated. But the effusion of lymph is more characteristic. This may be produced by natural inflammation as well as by irritating poisons. As arising from either cause, however, it is rare; and certainly by no means so common as would be supposed from what is said in systematic works; for tough mucus has been often mistaken for it. ”

“ Cold mucus from the throat. Much mucus, of rather a saline taste, and less inspissated than usual, is evacuated from the fauces by hawking, owing to the deficient absorption of the thinner parts of it. This becomes a habit in some elderly people, who are continually spitting it out of their mouths; and has probably been brought on by taking snuff, or smoking tobacco; which by frequently stimulating the fauces have at length rendered the absorbent vessels less excitable by the natural stimulus of the saline part of the secretion, which ought to be reabsorbed, as soon as secreted. ”

“ All mechanical obstructions to the free transit of blood through the heart, lungs, or liver are followed by the same results. A free secretion of mucus into the stomach is one of the most commonly recognized. It is often vomited in large quantities. This alkaline mucus, while it dilutes the digestive juices of the stomach, furnishes favorable conditions for the development of low micro-organisms, which contribute to the fermentative process. We may not duly estimate the effects of these organisms on a mucous membrane softened by long-continued passive hyperæmia. ”

“ The mucous membrane in the chronic state of the disease presents a rather dry, indolent and bluish appearance, except that here and there the tissues show more activity of the disease, more especially so over the anal region, due to harsher disturbance during the act of stooling. In the subacute or acute stage of the inflammatory process there is more general redness and puffiness of the mucous membrane, or a swollen condition with increased discharge of mucus and perhaps some blood. ”

“ Pus and mucus are both soluble in the vitriolic acid, though in very different proportions, pus being much the less soluble. 2. The addition of water to either of these compounds decomposes it; the mucus thus separated, either swims on the mixture, or forms large flocci in it; whereas the pus falls to the bottom, and forms on agitation a uniform turbid mixture. 3. ”

“ It is only in persons who labour under chronic debility, that a hæmoptysis is necessarily followed by consumption.
3. I yield to the popular mode of expression when I speak of a consumption being produced by tubercles. But I maintain that they are the effects of general debility communicated to the bronchial vessels which cause them to secrete a preternatural quantity of mucus. This mucus is sometimes poured into the trachea from whence it is discharged by hawking, more especially in the morning; for it is secreted more copiously during the languid hours of sleep than in the day time. ”

“ Of this many die, who have drank much vinous spirit, and some of them recover by voiding a quantity of white mucus, like chalk and water; and others by voiding a great quantity of sand, or small calculi. This hardened mucus frequently becomes the nucleus of a stone in the bladder. The salts of the urine, called microcosmic salt, are often mistaken for gravel, but are distinguishable both by their angles of crystallization, their adhesion to the sides or bottom of the pot, and by their not being formed till the urine cools. ”

“ Microscopical examination of the desquamated intestinal membrane and mucus from a man forty years of age, revealed the following products: crystals, mostly complete; incomplete phosphates, very numerous; mucous shreds in abundance; fat globules and granules, numerous; anal epithelia; red blood globules, few; connective tissue, scanty; pus corpuscles, very few; margaric acid and detritus (substances resulting from the destruction or wearing away of the part) ; undigested material, mostly cellulose; leptothrix threads, micrococci; and the bacillus coli communis. ”

“ Mucus, which is the chief product of this condition, leads to indigestion and fermentation of the intestinal contents and to increased irritation of the mucous membrane. The evolved gas distends the bowel and weakens its contractile power. The fecal mass when it reaches the rectum has an excess of mucus within it or around it which makes its expulsion more difficult. But the diminution or absence of bile does not constipate. In simple jaundice diarrhoea is not uncommon, and an excess of bile does not of necessity cause diarrhoea.6
5 Leube, in Ziemssen's Cyclopædia, vol. ”

“ When an inflammation has lasted for such a length of time that it has become chronic, a new tissue will sooner or later be produced in varying amount; and this newly formed fibrous connective tissue may entirely replace previous normal structures. Through the exudation and consequent changes in the normal tissue a large amount of mucus is at first secreted, but this secretion becomes less and less marked the more the inflammation causes a desquamation of the epithelia. ”

“ First, other congeries of glands occupy but a particular part of the system, or constitute a particular organ, as the liver, or kidneys; but those glands, which secrete the mucus, and perspirable matter, which are called capillaries, are of very great extent; they receive the blood from the arteries, separate from it the mucus, which lines every cell, and covers every cavity of body; and the perspirable matter, which softens and lubricates the whole surface of the skin, and the more extensive surface of the air-vessels, which compose the lungs. ”

“ Secretion of the Lungs.—Like the lips and mouth, the lungs are invested on their free inner surface by a delicate mucous membrane, which constantly secretes a clear viscous fluid, the mucus. The lungs, therefore, like the nose, are always moist, and just as the nose is cleared by blowing it, so the lungs are cleared by hawking or coughing. A sense of discomfort or a feeling of irritation of the windpipe induces a deep inspiration, followed by an explosive expiration, which quickly brings up the mucus, so that it can be expectorated. ”

“ Microscopically the bronchi show hyperaemia of the mucous and sub mucous coats, and the whole wall becomes infiltrated with polymorphonuclear leukocytes and round cells- Many cells undergo mucoid degeneration, and there is abundant epithelial proliferation. A large quantity of mucus is secreted by the glands, and the lumen of the bronchi contains an exudate consisting of mucus, degenerated leukocytes and cast-off epithelial cells. ”

“ The intestinal contents consist usually of tenacious, slimy mucus intermingled with thick green fecal matter; fæcal matter may be absent, and merely blood-stained mucus resembling frog's spawn, or, on the other hand, solid fæces, may be found. Intestinal adhesions may occur, but perforation is extremely rare. The microscopic pathology varies with the severity of the lesions. In the gangrenous form the epithelial cells of the mucous layer can no longer be distinguished, the whole of the mucous membrane undergoing coagulation necrosis with destruction of the glandular elements. ”

“ In this disease there appears to be a deficient absorption of the subcutaneous mucus, as well as inflammation and increased secretion of it. For the fluid not only excoriates the parts in its vicinity by its acrimony, but is very saline to the taste, as some of these patients have assured me; I believe this kind of eruption, as well as the tinea, and perhaps all other cutaneous eruption, is liable to be inoculated in other parts of the body by the finger-nails of the patients in scratching themselves.
It is liable to affect the hands, and to return at distant periods ”

“ If large quantities of mucus are vomited from time to time, especially in the morning, we may resort with benefit to the use of other astringents, such as bismuth, oxalate of cerium, kino, and opium; and if we have reason to suspect stricture of the pylorus in connection with a catarrhal condition of the mucous membrane, the stomach-pump gives the patient great relief. ”

“ On the second or third day the expectoration becomes bloody. Each sputum, spit, or crachat of the French is composed of mucus intimately combined with blood—that is, not simple streaks or striæ of blood, as in catarrh; nor is it pure blood, as in hemoptysis. Each sputum is either of a yellow, or rusty, or even red color, according to the quantity of blood intimately mixed with the mucus. ”

“ If liquids washed away the mucus from the mucous membrane, the throats of many individuals ought to be very harsh and dry, inasmuch as six to eight glasses of liquids pass through their mouths and throats during every day of twenty-four hours. ”

“ Thirdly, comes a point at which mucus is thrown out in large quantities to protect the gut, and this continues and increases until the actual cells themselves are shed, and the protection breaks down. ”

“ Mucus, mū′kus, n. the slimy fluid from the nose: the viscous fluid secreted by the mucous membrane of animals.—adjs. Mūcif′erous; Mūcif′ic; Mū′ciform.—n. Mū′cigen, a substance secreted by the cells of mucous membrane, converted into mucin.—adjs. Mūcig′enous, Mūcip′arous, secreting mucus.—n. Mū′cilage, the solution of a gum in water: the gum extracted from plants.—adj. Mucilag′inous, pertaining to, or secreting, mucilage: slimy.—n. Mū′cin, an alkaline glutinous fluid forming the chief constituent of mucus.—adjs. Mūciv′orous, feeding on the juices of plants ”

“ But as these are formed by the indurated mucus of the intestines alone without the urinary salts, it is probable a difference would be found on their analysis.
As the stones of the bladder are of various degrees of hardness, and probably differ from each other in the proportions at least of their component parts; when a patient, who labours under this afflicting disease, voids any small bits of gravel ”

“ But the inside of the body also has a skin, as have all its organs. The interior of the head, the throat, the gullet, the lungs, the stomach, and all the intestines, are lined with a skin. This is called the mucous membrane, because it is constantly secreting from the blood a slimy substance called mucus. When it accumulates in the lungs, it is called phlegm. This inner skin also has nerves, blood-vessels, and lymphatics. ”

“ These glands are very apparent in the bronchia, palate, the œsophagus and the intestines, in which they take the names of the anatomists who have accurately described them, and where they make in many places evident projections upon the mucous surface. They are less apparent in the bladder, the womb, the gall-bladder, the vesiculæ seminales, &c.; but the mucus that moistens them clearly demonstrates their existence. ”

“ In the diabætes, where the thirst is very great, this slough adheres more pertinaciously, and becomes black or brown, being coloured after a few days by our aliment or drink. The inspissated mucus on the tongue of those, who sleep with their mouths open, is sometimes reddened as if mixed with blood, and sometimes a little blood follows the expuition of it from the fauces owing to its great adhesion. ”

“ He tells us that—
“Soon after salivation has been established, the blood exhibits an inflammatory crust; at a later period its colour deepens, and its coagulability is diminished; the proportion of clot, and, therefore, of fibrin, to serum (or watery part) becomes smaller; the formation of albumen and mucus sinks to that of serum; the whole organic formation of the patient is less consistent and cohesive.” ”

“ Where the lungs or urethra are inflamed to a considerable degree, and the absorption is so great, that the mucus is already too thick, and adheres to the membrane from its viscidity, opiates and bitter vegetable and austere acids are improper ”

“ We frequently observe an unusual quantity of mucus or other fluids in some diseases, although the action of the glands, by which those fluids are separated from the blood, is not unusually increased; but when the power of absorption alone is diminished. ”

“ Following the previous general arguments to the effect that mucus is the main cause of disease and ageing, there is only left to show in particular and on the various organs in how far the mucus of culture-food acts beauty-hindering in the construction of the human body, and produces symptoms of ugliness and age. ”

“ Each “physiological machine,” man like beast, cleanses itself immediately, dissolves the mucus in the clogged-up vessels, without stopping short, as soon as the supply, of compact food at least, is interrupted. Even in the case of the supposedly healthiest man this mucus, as already mentioned then appears in the urine where it can be seen after cooling off in the proper glass tubes! ”

“ The mucus of the lungs becomes hardened by the increased absorption, so that it adheres and forms a kind of lining in the air-cells, and is sometimes spit up in the form of branching vessels, which are called polypi of the lungs. ”

“ The changes are less marked, perhaps, in the trachea than in its finer ramifications. The mucosa is constantly more or less destroyed and large areas, usually focal, are entirely devoid of their epithelial covering. This is replaced by a sparse exudate, composed largely of red blood cells, mucus, a small amount of fibrin, and nuclear fragments (Fig. II) . It may dip into the submucosa for a short distance, but usually these indentures are associated with the ducts of the mucous glands into which the inflammatory reaction extends. ”