Pestilence, a term referring to a devastating disease or epidemic, has long symbolized both physical and moral decline in literature. Authors such as Nathaniel Hodges, John Caius, and Thomas De Quincey examined its dual role as a tangible affliction and a metaphor for societal or spiritual decay. Hodges portrayed plague as a force that magnifies human vulnerability, while Caius described the medieval dread of its spread, presenting it as divine judgment.
De Quincey connected pestilence to cosmic punishment, reflecting biblical depictions of divine anger. These differing viewpoints highlight how pestilence, whether real or symbolic, has functioned as a means to explore human frailty, ethical shortcomings, and the relationship between nature and fate.