Anion

“ Chemists, as we have said, understand by organic radicals certain groups of atoms of carbon and hydrogen, which are capable of combining with an atom of hydrogen in the same manner as an atom of bromine, or iodine, or chlorine, or which may be substituted for an atom of one of these substances in one of its combinations. In a complex body like rosaniline, one or more atoms of hydrogen may be removed and replaced by as many atoms of the organic radical. MM. Girard and De Laire caused aniline to react upon rosaniline. Aniline is an organic base, an ammoniacal compound. ”

“ For the ordinary purposes of analysis, requiring the precipitation of say one milligram of any ion from 100 c.c. solution (one-tenth per cent, if one gram of substance is used for analysis) , a concentration of hydrogen-ion of 0.1 to 0.3 gram-ion per liter forms a good basis for work.421 The presence of this concentration of hydrogen-ion, irrespective of the possible presence of weak organic or inorganic acids, may be readily insured by a simple test with an appropriate indicator. ”

“ Sometimes an ion is combined with a protein, for instance, or with other substances, and so is robbed of its own characteristics; at other times an ion is set free through decomposition or simple dissociation. ”

“ The whole fabric of chemistry rests, even at the present day, upon the opposition of acids and bases: an acid was certainly at first known by its sensible qualities, and how otherwise, even now, do we perceive its quality? It was a great discovery of modern times that earths and alkalies have for their bases metals: but what are metals? or how, except from lustre, hardness, weight, and the like, do we recognize a body as a metal? And how, except by such characters, even before its analysis, was it known to be an earth or an alkali? ”

“ To eliminate the last traces of ammonia, we place for a few minutes the vessel containing the alkaloid in a vacuum over sulphuric acid, and obtain the organic alkaloid with the chemical and physical characters which belong to it, and which it is now the Chemist’s duty to determine positively. ”

“ As experimental discovery advanced, the substances classed with acids have been constantly multiplying, and by a natural consequence the attributes connoted by the word have receded and become fewer. At first it connoted the attributes, of combining with an alkali to form a neutral substance (called a salt) ; being compounded of a base and oxygen; causticity to the taste and touch; fluidity, etc. The true analysis of muriatic acid, into chlorine and hydrogen, caused the second property, composition from a base and oxygen, to be excluded from the connotation. ”

“ Properties of Acids and Alkalis.—The name acids is given to a class of substances, mostly soluble in water, having an acid or sour taste, and capable of turning blue litmus solution red. All acids contain one or more atoms of hydrogen capable of being replaced by metals, and when such hydrogen atoms are completely replaced by metals, there result so-called neutral or normal salts, that is, neutral substances having no action on litmus solution. ”

“ Organic acids, either in free form, or partially neutralized with calcium, potassium, or sodium, forming acid salts, or combined with various alcohols in the form of esters, are widely distributed in plants. ”

“ Inspection of the equation for acetic acid, which is the typical equilibrium equation for all monobasic acids, shows that the greater the degrees of ionization of acids are in equivalent solutions, i.e. the greater the concentrations of the hydrogen-ion which their ionization produces in equivalent solutions, the larger will be the values of their ionization constants. The acids with the larger constants are, then, the stronger acids. ”

“ Carbon, hydrogen, and oxygen, plus varying proportions of phosphorus, potassium, iodine, nitrogen, sulfur, calcium, iron, magnesium, manganese, and strontium, plus a smattering of trace elements, seem to be able to cook up all kinds of life under the strangest imaginable conditions. ”

“ It becomes extremely easy, from the principles laid down in the preceding chapter, to establish a systematic nomenclature for the acids: The word acid, being used as a generic term, each acid falls to be distinguished in language, as in nature, by the name of its base or radical. Thus, we give the generic name of acids to the products of the combustion or oxygenation of phosphorus, of sulphur, and of charcoal; and these products are respectively named, the phosphoric acid, the sulphuric acid, and the carbonic acid. ”

“ When we attempt to ascertain the relative preserving power of the neutral salts, it will appear that those whose acid forms with the lead a soluble salt of lead are the least energetic; while those whose acid forms an insoluble salt of lead are most energetic. The protecting powers of acetate of soda, nitrate of potass, muriate of soda, sulphate of lime, arseniate of soda, and phosphate of soda, are inversely as the solubility of the acetate, nitrate, muriate, sulphate, arseniate, and phosphate of lead. ”

“ I am quite convinced that every Chemist who has kept up his knowledge as to analysis, will not only succeed in detecting their presence, but even in determining the nature of that which he has discovered, provided that the alkaloid in question is one of that class of bodies, the properties of which have been suitably studied. Thus he will be able to discover conia, nicotine, aniline, picoline, petinine, morphine, codeine, narcotine, strychnine, brucine, veratrine, colchicine, delphine, emetine, solanine, aconitine, atropine, hyoscyamine. ”

“ Some chemists have supposed that there must be a base united to the mercury, and have named this hypothetical substance “ammonium,” to correspond to potassium and sodium, the bases of potash and soda, which resemble ammonia in so many properties. But what is this ammonium? and how is it formed? for hydrogen and nitrogen are simply elementary bodies. Are all metals compounds of gases? ”

“ An inquiry of the kind is, from the analytical point of view, tedious and often difficult; for though the analytical chemist can easily and quickly identify the nature of inorganic salts in a mixture or powder, and estimate their amount, most vegetable drugs which exert any appreciable effect on the body owe their power to the presence of an alkaloid or glucoside. The active principle of opium, for instance, is morphine; that of cinchona bark, quinine; that of belladonna, atropine, and so on, and the chemist can recognise any alkaloids present in a mixture or pill. ”

“ Compounds of the first type constitute the vegetable bases; while those of the second type are the proteins.
The vegetable bases may be divided into three groups. These are (a) the plant amines, which are simple open-chain amines; (b) the alkaloids, which are comparatively simple closed-ring amines, containing only one nitrogen atom in any single ring; and (c) the purine bases, which are complex compounds containing a nucleus with four carbon atoms and four nitrogen atoms arranged alternately to form a double-ring group. ”

“ Acids may be considered as a peculiar class of burnt bodies, which during their combustion, or combination with oxygen, have acquired very characteristic properties. They are chiefly discernible by their sour taste, and by turning red most of the blue vegetable colours. These two properties are common to the whole class of acids; but each of them is distinguished by other peculiar qualities. Every acid consists of some particular substance, (which constitutes its basis, and is different in each,) and of oxygen, which is common to them all. ”

“ Some natural alkaloids contain carbon, hydrogen, and nitrogen only; these are, for the most part, liquid at ordinary temperatures, and can be distilled without decomposition. The greater number of the artificial alkalies are composed of carbon, hydrogen, and nitrogen; some, however, contain oxygen in addition. Alkaloids have also been obtained artificially, in which nitrogen is replaced by phosphorus, arsenic, antimony, or bismuth. Most of the alkaloids, as they are obtained in the free state, correspond in function to ammonia, NH3, rather than to the fixed alkalies ”

“ Again, if in wood spirit we substitute an atom of oxygen for 2 of the remaining atoms of hydrogen we obtain formic acid, CHO.OH, the first of a long series of acids, of which the second, corresponding to ordinary alcohol, is acetic acid, and the highest members, such as stearic acid, C18H35O.OH, are solid fats. ”

“ N/10 acid per 100 c.c., are too great if made up by taking a solution of the free acids. The ionization must be almost entirely repressed by the presence of sufficient neutral salts of the same acids in the bating liquid, in order to obtain a similar result to the puer. ”

“ With nitrogen, hydrogen unites and forms one of the most extraordinary compounds in the whole range of chemistry,—the gas called ammonia. This is the only gas possessing what are called alkaline properties; i.e., it changes the blue color of certain vegetables to green, yellow to deep brown, and unites with the acids to form neutral compounds, just as the other alkalies, potash and soda, which are oxides of metals. ”

“ The first class includes such substances as iodine, mercury, iron, carbon, and their various compounds, and such bodies as alcohol, chloroform and chloral, all of which are found in nature or can be prepared by ordinary chemical processes of manufacture. From plants many substances are obtained which at the present time we are unable to make in the chemical laboratory, and of the constitution or composition of which we are in many cases ignorant. ”

“ Raw Onions contain an acrid volatile oil, sulphur, phosphorus, alkaline earthy salts, phosphoric and acetic acids, with phosphate and citrate of lime, starch, free uncrystallized sugar, and lignine. The fresh juice is colourless, but by exposure to the air becomes red. A syrup made from the juice with honey is an excellent medicine for old phlegmatic persons in cold weather, when their lungs are stuffed, and the breathing is hindered. ”

“ Compare those sets of symbols, and tell me honestly if you—without the assistance of a chemical expert—could say offhand which represents, say, creatine, the crystalline substance which is contained in your own muscles at this present moment, and the high explosive which goes by the name of devastite. Consider again that the very air we breathe consists of four-fifths of nitrogen—and it is scarcely necessary to remind a man occupying your post that nitrogen forms the basic principle of almost every explosive known. ”

“ A second method of exciting the stomach into action, and of decreasing that of the capillaries in consequence, is by the stimulus of wine, opium, bark, metallic salts of antimony, steel, copper, arsenic, given in small repeated quantities; which so long as they render the pulse slower are certainly of service, and may be given warm or cold, as most agreeable to the patient. ”

“ The quantity of opium was then gradually decreased, but not totally omitted, as he continued to take about a grain morning and evening.
January 17.—He makes fourteen pints of water a day. Dr. Underhill now directed him two scruples of common rosin triturated with as much sugar, every six hours; and three grains of opium every night.
19.—Makes fifteen pints of water: sweats at night.
21.—Makes seventeen pints of water; has twitchings of his limbs in a morning, and pains of his legs: he now takes a dram of rosin for a dose, and continues the opium. ”

“ AMINES, in chemistry, derivatives of ammonia in which one or more of the hydrogen atoms are replaced by alkyl or aryl groups. The replacement of one hydrogen atom by one alkyl or aryl group gives rise to primary amines; of two hydrogen atoms by two groups, to secondary amines; of three hydrogen atoms by three groups, to tertiary amines. The tertiary amines possess the power of combining with one molecular proportion of an alkyl iodide to form quaternary ammonium salts. ”

“ Methods of determining the migration velocity of the ions have been worked out by Hittorf, Kohlrausch, Lodge, and others.
Svante August Arrhenius.
The theory of ionisation affords a satisfactory180181 explanation of many chemical phenomena. It accounts for the characteristic properties of acids, and explains why different acids have varying “strengths” and why a “weak” acid has the same “strength” as the “strong” acid at high equivalent dilutions: in each case the acid is nearly completely ionised—in other words, the “strength” of an acid depends on the concentration of its hydrogen ions. ”

“ The sulphate, muriate, nitrate, acetate of morphia all act like opium. Strychnia, arsenic, hydrocyanic acid, oxalic acid, and many more come under the same denomination: Each produces its peculiar effects, with whatever substance it is combined, provided it do not become insoluble. ”

“ Neither the strong acids nor alcohol, when considerably diluted, occasion any disturbance in it; but sulphuric æther and its compound spirit, the tincture of muriated iron, and sub-acetate of lead, produce very dense precipitates: the acetate of lead only occasions decomposition, when an alkaline salt is present in the formula; the volatile alkali curdles the mucilage, and hard calcareous waters render the mixture difficult and often impracticable. ”

“ Action of Sulphuric Acid on the insoluble residue left by Opium, exhausted by water. Formation of a new Alkaloid, by M. STANISLAS MARTIN.—The smallest object added to a kaleidoscope produces new shades and different images; so it is {319} with vegetable chemistry; every practical man knows that a foreign body, an hours delay in executing a work already commenced, changes the nature of the products. Two experiments on the inert residue of opium, exhausted by water give another illustration of this truth. ”

“ Aniline Black.—Water, 20 to 30 parts; chlorate of potassa, 1 part; sal ammoniac, 1 part; chloride of copper, 1 part; aniline and hydrochloric acid, each 1 part, previously mixed together. It is essential that the preparation should be acid, and the more acid it is the more rapid will be the production of the blacks; if too much so, it may injure the fabric. ”