Patrick Manson,
Tropical Diseases
(1919)
“ Intermittent fever or ague.—— Every typical malarial fever is made up of a series of pyrexial attacks which recur at definite intervals of twenty-four, forty-eight, or seventy-two hours. Each attack consists of a stage of rigor, a stage of heat, and a stage of sweating; these are followed by a period, " the interval," of apyrexia -actual or relative. The duration and intensity of the constituent stages vary considerably. On the whole, they observe a certain proportion to each other; as a rule, the more pronounced the rigor, the higher the fever and the more profuse the sweating. ”
