Seminal vesicle

“ Congestions, irritation and even inflammation of the Urinary Organs often occur in men, either alone or as a complication of Seminal Disease and Weakness. The Seminal Vesicles lie just behind the bladder, while the Seminal Ducts pass through the body of the Prostate Gland, and open into the urethra (or urine channel) upon its surface (see Fig. 5) . Hence, any inflammation or congestion of this large gland that lies at the root of the organ and neck of the bladder, is almost certain to produce Seminal Weakness, Losses and Impotence. ”

“ According to most recent writers, the seminal vesicles of mammals are receptacles for their own albuminous secretion, the function of which is unknown. Steinach could find no spermatozoa in these "seminal" sacs, and therefore he proposed to use Owen's name of glandulæ vesiculares. After extirpation of these vesicular glands in the white rat typical coitus occurred. But the capacity for procreation was diminished, and extirpation of both glandulæ vesiculares and glandulæ prostaticæ led to disappearance of the capacity for procreation. ”

“ During the secretion of the spermatozoa the nerve apparatus of the genital system is charged with vital energy. When the tension becomes very high, which coincides with the filling of the vesicles with sperma, the nervous tension and the physical pressure are both eager to discharge, respectively, to evacuate. When the bladder and rectum are filled during the night, their pressure upon the seminal vesicles becomes so great that the latter evacuate and thus cause an ejaculation and a change both in blood and nerve-supply. ”

“ On the occasion of the next nocturnal emission the ampullæ will empty along with the seminal vesicles and these spermatozoa pass out. If they be examined under the microscope as a part of a normal nocturnal emission, they will be found to be almost motionless or very greatly lacking in typical spermatozoon activity. ”

“ In those cases it is not the physical effect of any loss of seminal fluid that is the disturbing factor of their health, but their worry over the losses. Just as soon as their minds can be taken off the subject, the supposed physical effects begin to disappear. So long as the solicitude continues the emissions themselves increase in number and the condition is made worse. These patients must be taught that in every normal healthy man in whom there is no regular occasion for the emptying of the seminal vesicles, nature provides for an evacuation about every ten days or two weeks. ”

“ The Vesiculæ Seminales appear like two cellular bags. They have two coats, the one called nervous, and the inner the cellular, a membrane divided into folds or ridges. The use of the vesiculæ is supposed to be, to act as reservoirs for the semen; but there are different opinions upon the subject, some contending that they furnish a fluid, not spermatic, but merely as an addenda to the seminal secretion; whereas others, who have examined the vesiculæ of persons who have suddenly died, have discovered all the essential qualities of the male seed therein ”

“ A little bladder-like body, not larger than a pea, is often found hanging by a thread-like stalk from one of the fimbriæ of the oviduct. It is a relic of foetal life, being probably the remains of the Wolffian body, and sometimes goes by the name of the hydatid or vesicle of Morgagni. The walls are very thin and covered by peritoneum. What rôle these vesicles play in the economy is uncertain, but they have been found to undergo cystic degeneration. They rarely attain to a size larger than that of an orange, and then either remain stationary or else burst. ”

“ In science, we have to consider two things: power and circumstance. All we know of the egg, from each successive discovery, is, another vesicle; and if, after five hundred years, you get a better observer, or a better glass, he finds within the last observed another. In vegetable and animal tissue, it is just alike, and all that the primary power or spasm operates, is, still, vesicles, vesicles. Yes—but [Pg 276] the tyrannical Circumstance! A vesicle in new circumstances, a vesicle lodged in darkness, Oken thought, became animal; in light, a plant. ”

“ The ovum, enclosed by the zona radiata, passes into the Fallopian tube and undergoes a segmentation which has not been studied with great detail. On the close of segmentation, about six days after impregnation, it assumes (Hensen) a vesicular form not unlike that of other Mammalia. To the inner side of one wall of this vesicle is attached a mass of granular cells similar to the hypoblastic mass in the blastodermic vesicle of the rabbit. The egg still lies freely in the uterus, and is invested by its zona radiata. ”

“ The epithelium may separate from the stratum basale, leaving a red lesion with shreds of torn epithelium. Vesicular fluid may leak through the stratum corneum without the formation of a true vesicle (Seibold and Sharp 1960) . Since vesicles are most often seen at the site of mechanical stress, they usually rupture quickly, leaving a red erosion. Often, lesions are contaminated with dirt and debris (Fig. 25.2) , resulting in infection with opportunistic bacteria. ”

“ No doubt they alone do not supply a sufficient basis for any firm conclusions as to the fate of the germinal vesicle. Still, if they cannot sustain, they unquestionably support certain views. The natural interpretation of them is that the membrane of the germinal vesicle is in the act of commencing to atrophy, preparatory to being extruded from the egg, while the contents of the germinal vesicle are about to be absorbed. ”

“ Its outer layer « 60 » is clear or transparent, and more dense than the inner mass, which seems granular. It has at one end a curious vesicle which can be seen gradually to expand and become filled with a clear drop of liquid, and then suddenly to contract and expel the contained fluid through a series of pores in the adjacent part of the outer wall. This is the so-called pulsating vesicle, and is an organ both of circulation and excretion. In another part of the body may be seen the nucleus, which is a little cell capable, at certain times, of producing by its division new individuals. ”

“ Fig. 62. Section through the trunk of a Lepidosteus embryo on the sixth day after impregnation.
mc. medullary cord; ms. mesoblast; sg. segmental duct; ch. notochord; x. subnotochordal rod; hy. hypoblast.
With reference to the features in development, visible in sections, a few points may be alluded to.
[Pg 115] The optic vesicles are very prominent outgrowths of the brain, but are still solid, though the anterior cerebral vesicle has a well-developed lumen. The auditory vesicles are now deep pits of the nervous layer of the epiblast, the openings of which are covered by the epidermic layer. ”

“ All three operations were successful, and on the eighth day all three vesicles were matured “like a pearl upon a rose petal,” as Jenner described a perfect specimen. On that day, the eighth day after the operation, I visited my patient, and to all appearance she was in the soundest health and spirits, with her usual bright eyes and ruddy cheeks. Although I was much tempted to take the lymph from so healthy a vesicle and subject, I did not do so, as I have frequently seen erysipelas and other had consequences follow the opening of a matured vesicle. ”

“ Before Schwann had published his classical memoir in 1839, von Baer and other observers had recognized within the animal ovum the germinal vesicle, which obviously bore to the ovum the relation of a nucleus to a cell. As the methods of observation improved, it was recognized that, within the developing egg, two vesicles appeared where one only had previously existed, to be followed by four vesicles, then eight, and so on in multiple progression until the ovum contained a multitude of vesicles, each of which possessed a nucleus. ”

“ Two of the stages in the formation of the secondary vesicle by this process of involution are shewn in Plate X, fig. A II , and A III. In the second of these the general growth has been very considerable, rendering the whole animal much larger than before. The cavity of this vesicle, A III , is that of the commencing alimentary canal whose final form is due to changes of shape undergone by this primitive cavity. The inner wall of the vesicle becomes converted into the wall of the alimentary canal or hypoblast, and also into part or the whole of the mesoblast. ”

“ Pie charts summarizing results of fields A and B concerning the reformation of SVs at different times after recovery. Entire pie: total SVs before stimulation; white sector: unlabeled SVs; black sector: labeled SVs after stimulation; striped section: total labeled SVs subtracted by the SVs formed during stimulation. ****, ***, **, * indicate p-values of <0.0001, <0.001, <0.01, and <0.05, respectively. N.D., ‘not determinated’. Black asterisks refer to comparisons between total vesicles, colored asterisks to comparisons between HRP-labeled vesicles. ”

“ The first symptoms indicative of the approaching efflux of blood occur on the Thursday, generally about noon. On each of the pink surfaces already described on the hands and feet, a vesicle is seen to commence, and to rise little by little. When completely developed, it is a rounded hemispherical prominence on the surface of the skin; its base is the same size as the pink surface on which it rests—that is, nearly an inch long, by a little more than half an inch broad. This vesicle is formed by the epidermis detached from the dermis, and elevated as a half sphere by serous liquid within. ”

“ Synaptic vesicles (SVs) are the specialized organelles that store and secrete non-peptide neurotransmitters at synapses. Following exocytosis, their membranes are rapidly recaptured by endocytosis and recycled for the generation of new fusion-competent SVs ( [1] ; [2] ; [3] ) . Strong evidence indicates that clathrin-mediated endocytosis (CME) plays a key role in this endocytic traffic ( [2] ; [4] ; [5] ; [6] ; [7] ; [8] ) . Endocytic vesicles generated by CME have a small homogenous size, in the same range of SVs ( [9] ; [10] ) . ”

“ The blastodermic vesicle has at first the usual spherical form, but it grows out at an early period, and with prodigious rapidity, into two immensely long horns; which in cases where there is only one embryo are eventually prolonged for the whole length of the two horns of the uterus. The embryonic area is formed in the usual way, and its long axis is placed at right angles to that of the vesicle. On the formation of an amnion there [Pg 251] is formed the usual subzonal membrane, which soon becomes separated by a considerable space from the yolk-sack (fig. 153) . ”

“ He found in the impregnated, but not yet segmented, germinal disc a cavity which, as he suggests, might well have been occupied by the germinal vesicle. It is not unreasonable to suppose that the membrane, being composed of formed matter and able only to take a passive share in vital functions, could, without thereby influencing the constitution of the ovum, be ejected. ”

“ The fluid continues to increase in amount until the papule is converted into a little blister or vesicle. As the change is going on, the height of the papule grows less and less, and when vesiculation is complete we have a broad, flat, umbilicated vesicle with a firm, dense base. ”

“ In most male batrachians the testes are drained by transverse canals which open into a longitudinal duct, which also receives the canals of the kidneys, so that this common duct conveys both sperma and urine. In some of the discogloesid frogs, however, the seminal duct is quite independent of the kidney, which has its own canal, or true ureter. Many of the Ecaudata have remnants of oviducts, or Müllerian ducts, most developed in Bufo, which genus is also remarkable as possessing a problematic organ, Bidder’s organ, situated between the testis and the adipose or fat-bodies that surmount it. ”

“ In about twelve minutes a well-developed circular vesicle was obtained, filled with transparent serum. On the hypothesis of fraud, this should have burst spontaneously; but, as it did not do so, it was ruptured and the cuticle torn off, thus exposing two raw surfaces side by side, upon the same hand, and involving the same tissues. The two spots were carefully watched; the stigma continued to bleed freely for two hours and a half longer, while the blistered surface during this period did not yield a single drop of blood. ”

“ They all assume the ordinary cell character, with outer and inner sac,—the inner sac forming on the side, like the Purkinjean vesicle itself; but it does not retain this position, for, as soon as its wall is formed and it becomes a distinct body, it floats away from the side and takes its place in the centre. Next there arise within it a number of little bodies crystalline in form, and which actually are wax or oil crystals. They increase with great rapidity, the inner sac or mesoblast becoming sometimes so crowded with them, that its shape is affected by the protrusion of their angles. ”

“ The testes, epididymes, vesicles, prostate, and other parts, each contribute their essential part to the semen, abnormalities of any one of which, as a rule, result in interferences with reproduction. If the vesicles are involved, we must bear in mind just what is the part played by their secretion, and what is the probable result if their essential elements are not added to the semen. In like manner, we must consider the prostate, whose secretion stimulates the vitality of the sperms, and adds fluid bulk to the semen. ”

“ These invaginated cells are the arch-enteron; they proliferate and give off branching cells, which apply themselves (fig. 25, C) to the inner face of the vesicle, thus forming the mesoblast. The outer single layer of cells which constitutes the surface of the vesicle is the ectoderm or epiblast. The little mass of hypoblast or enteric cell-mass now enlarges, but remains connected with the cicatrix of the blastopore or orifice of invagination by a stalk, the rectal peduncle. The enteron itself becomes bilobed and is joined by a new invagination, that of the mouth and stomodaeum. ”