Chemical reagent

“ Other condensing reagents of value are aceto-acetic ester, sodium amalgam, sodamide, sodium ethoxide, dimethyl sulphate, zinc chloride, aluminium chloride, fused caustic potash, hydrogen chloride, phenyl-hydrazine, hydrogen peroxide in presence of a ferrous salt (Fenton’s reagent) , ammonia, and various amines. The application of these reagents has led to the discovery of a variety of new compounds, the mode of origin of which has served to elucidate their constitution. ”

“ The size of the pieces must be adapted to the penetrating power of the fixing reagent, but as a rule the pieces should not be more than 2-3 cms. in thickness, and for some reagents 0.5 cm. is as thick as they can safely be. The reagents used should be changed when they become cloudy or discolored. The used solution may be filtered and used again, but some reagents can be used but once. Alcohol may be saved for redistillation. In the case of some reagents (mercuric chloride, chromic acid, osmic acid, etc.) ”

“ Every operator should be provided with a bottle of ammonia, as a little sprinkled about the chemical room soon disinfects it of all iodine or bromine vapor, and also tends to facilitate the operation in the camera. ”

“ Bayliss defines enzymes as the “catalysts produced by living organisms.” A catalyst is a body which greatly accelerates the rate of reaction in chemical processes, without apparently taking part in the process. For instance, peroxide of hydrogen is decomposed into oxygen and water by mere contact with finely divided platinum, while the latter remains unaltered in the process. ”

“ If brought into contact with a solution of some substance which will withdraw the hydroxyl ions, converting them into water, or into some non-ionized substance, they are replaced at the expense of the molecules of non-ionized ammonium hydroxide; and these, when diminished in amount, draw on the store of molecules of ammonia and water, which combine, so as to maintain equilibrium, Now the investigation of such changes must belong to the domain of inorganic chemistry. It is true that the methods of investigation are borrowed from the physical chemist ”

“ Acids and bases appear to act catalytically upon all reactions involving consumption or liberation of water, and indeed that action is proportional to the concentration of the hydrogen or hydroxyl-ions. Further, the decomposition of hydrogen peroxide is “catalysed” by iodine-ions, the condensation of two molecules of benzaldehyde to benzoin by cyanogen-ions. One of the earliest known and technically most important instances of catalysis is that of the oxidation of sulphur dioxide to sulphuric acid by oxygen in the presence of oxides of nitrogen. ”

“ Hence, reactions between organic compounds, even when they are in solution, proceed very slowly unless carried on at high temperatures, under increased pressure, or under the influence of some catalytic agent. Even under the stimulation of these reaction-accelerating agencies, most chemical changes in organic compounds when carried on in the laboratory, require several hours or even days and sometimes weeks, for their completion. But when similar reactions take place in living organisms, they proceed with velocities which resemble those of inorganic compounds in the laboratory. ”

“ We may thus compare the effect of the reagent in relation to the normal effect of water or dilute NaCl solution. There is again an extremely delicate method of comparison of the relative effects of a series of compounds like Na2CO3, K2CO3, &c. Balance having been previously obtained between the normal sensitiveness of A and B, the two different solutions are now applied at the two points; the slightest difference in their relative action is at once exhibited by. the upsetting of the balance during stimulation, the direction of the resultant deflection indicating the more exciting reagent. ”

“ Inorganic end-products of putrefaction.
"5. Inorganic end-products of putrefaction: free nitrogen, ammonia, free hydrogen, methane, carbonic acid, methylmercaptan, sulphuretted hydrogen. It is probable also, but not certain, that phosphuretted hydrogen is formed and is oxidised at once by the free oxygen of the atmosphere.
Ptomaines.
"Most of these substances are formed also by the [Pg 61] chemical decomposition of proteids, but there is a sixth group which may be termed specific putrefactive products. These are the so-called ptomaines or putrefactive alkaloids. ”

“ Let us now take the case of the production of an aniline colour, and let us try to discover what aniline is, and how formed. I pointed to benzene or benzol in the table as a hydrocarbon, C6H6, which forms a principal colour-producing constituent of coal-tar. If you desire to produce chemical appetite in benzene, you must rob it of some of its hydrogen. ”

“ Since normal solutions of various reagents are all referred to a common standard, they have an advantage not possessed by empirical solutions, namely, that they are exactly equivalent to each other. Thus, a liter of a normal solution of an acid will exactly neutralize a liter of a normal alkali solution, and a liter of a normal oxidizing solution will exactly react with a liter of a normal reducing solution, and so on. ”

“ Arnot, who has considered this subject very thoroughly, says:—"I do not think there is much in this objection, as those agents that are soluble pass through the wire of the machine almost completely, while those that are insoluble are in the finest possible state of division and pearly white. The chemical agent most largely used is hyposulphite of soda, but hyposulphite of lime is also employed, and those agents, known by the name of 'antichlor,' are put into the engine in such a quantity as will ensure the neutralisation of the whole of the chlorine. ”

“ If a large number of observations are to be made, an acid may be prepared so that each c.c. equals 1 mgrm. of quinine. A reagent of general application is found in the so-called Mayer’s reagent, which consists of 13·546 grms. of mercuric chloride, and 49·8 grms. of iodide of potassium in a litre of water. Each c.c. of such solution precipitates—
The final reaction is found by filtering, from time to time, a drop on to a glass plate, resting on a blackened surface, and adding the test until no precipitate appears. ”

“ In organic as in inorganic chemistry, atoms are bound together by chemical affinity, though it was formerly supposed that an additional or vital force was instrumental in forming organic compounds. For this reason none of these substances, it was thought, could be built up in the laboratory, although many had been analyzed. In 1828 the first organic compound, urea, was artificially prepared, and since then thousands have been synthesized. They are not necessarily manufactured from organic products, but can be made from mineral matter. ”

“ Whether we have here an instantaneous action between non-ionized molecules, as claimed by the observer, or whether the minimal ionization157 of the hydrogen chloride and copper oleate, the existence of which we have a right to assume, is sufficient to account for this rapid action, both components being in solution and intimately mixed, is a question of the greatest interest. ”

“ Great success has also been obtained by “plate-towers” made of stoneware, which allow both the coke-towers and most of the stoneware receivers to be dispensed with.
3. Preparation of Chlorine.—In this place we speak only of the preparation of chlorine from hydrochloric acid by chemical processes; the electrolytic processes will be treated hereafter. It is clear that free chlorine must be prepared from hydrochloric acid by oxidizing the hydrogen. This can be done most easily by “active” oxygen, such as is present in the peroxides, in chromic or permanganic acid. ”

“ Ammonia escapes, giving all the reactions described under silk. Hence fur, wool, etc., contain nitrogen. As regards proofs of all three of these classes of fibres containing carbon, hydrogen, and oxygen, the char they all leave behind on heating in a closed vessel is the carbon itself present. For the hydrogen and oxygen, a perfectly dry sample of any of these fabrics is taken, of course in quantity, and heated strongly in a closed vessel furnished with a condensing worm like a still. You will find all give you water as a condensate—the vegetable fibre, acid water ”

“ The destruction of organic matter through simple distillation by means of pure hydrochloric acid is at least equal to that by sulphuric acid, chlorate of potash, and the carbonisation methods. The object of the chemist not being to dissolve every fragment of cellular tissue, muscle, and tendon, but simply all mineral ingredients, the less organic matter which goes into solution the better. ”

“ The stability constants, and the concentrations of the components used, determine the limiting concentrations in which a given metal ion is capable of continued existence, and determine, therefore, the question whether an ionogen, of a given solubility, is capable of existence as a solid phase in a given system. ”

“ Chemical Composition. When pure it consists of oxygen, hydrogen, and carbon; the rectified æther however still contains some water and alcohol, for Lovitz obtained an æther of 632. Solubility. One part requires for its solution ten of water; with alcohol and ammonia it unites in every proportion. Solvent Powers. It is one of 268the most powerful solvents known in vegetable chemistry, as it dissolves balsams, resins, gum-resins, wax, camphor, extractive, &c.; it takes up about a twentieth of its weight of sulphur, but it exerts no solvent power upon the fixed alkalies. Forms of Exhibition. ”

“ How might NH4Cl be obtained from the NH4OH in the Woulff bottles? (6) Test the liquid in each bottle with red litmus paper. (7) Add some from the first bottle to 5 or 10 cc. of a solution of FeSO4 or FeCl2, and look for a ppt. State the reaction.
99. Formation.—Ammonia, hartshorn, exists in animal and vegetable compounds, in salts, and, in small quantities, in the atmosphere. Rain washes it from the atmosphere into the soil; plants take it from the soil; animals extract it from plants. Coal, bones, horns, etc., are the chief sources of it, and from them it is obtained by distillation. ”

“ Regenerate the ion exchange column according to the instructions of the manufacturer. NOTE: All solutions must be made using ammonia-free water. 2. Sulfuric acid, conc., reagent grade. 3. Phenol. 4. Sodium hydroxide, reagent grade. 5. Brij-35. 6. Ammonium chloride. 7. Chloroform. 8. Sulfuric acid 5 N. Air scrubber solution (AAII) . Carefully add 140 mL of concentrated sulfuric acid to approximately 500 mL of ammonia-free distilled water. Cool to room temperature and dilute to 1 L with ammonia-free water. 9. ”

“ In the decomposition of animal substances, we perceive the union of hydrogen and nitrogen forming ammonia; the combination of carbon with oxygen produces carbonic acid; and nitric acid arises from the union oxygen and nitrogen. A quantity of hydrogen is also extricated in the form of gas, carrying off with it sulphur and phosphorus, which produce together the disagreeable smell arising from animal putrefaction. Nothing now remains but a portion of carbon mixed with phosphate of soda and phosphate of lime. ”

“ I know that in some places there are chemists who habitually find considerably more phosphoric acid and more ammonia in any given fertilizer than it actually contains. If a young chemist dares to find the amounts actually present, and to state the results, the manufacturer discards them, and takes the highest and false ones obtained by the initiated chemist. ”

“ Expert Analysis.—A modification of this experiment is employed by experts to test for AS2O3 poisoning. The organs.— stomach or liver—are cut into small pieces dissolved by nascent Cl, or HClO, made from KC1O3 and HCl, and the solution is introduced into a H generator, as above. AS2O3 preserves the tissues it comes in contact with, for a long time, and the test can be made years after death. All the chemicals must be pure, since As is found in small quantities in most ores, and the Zn, HCl, and H2SO4 of commerce are very likely to contain it. ”

“ The freshly prepared precipitate dissolves in nitric acid with a reddish colour; hydrochloric acid reduces it, with evolution of chlorine, and formation of cerous chloride, whilst sulphuric acid dissolves it with partial reduction, oxygen being evolved. If a solution of a ceric compound be dialysed for some days, a clear neutral solution is obtained, which contains the hydroxide in the colloidal condition; by evaporation of the solution, a gummy mass is obtained, which dissolves again in water to a clear solution. Electrolytes rapidly cause coagulation. ”

“ Erlenmeyer flasks, cover them with watch-glasses, and bring the acid just to boiling. Remove them from the flame and drop in the portions of wire, taking great care to avoid loss of liquid during solution. Boil for two or three minutes, keeping the flasks covered (Note 1) , then wash the sides of the flasks and the watch-glass with a little water and add stannous chloride solution to the hot liquid !from a dropper! until the solution is colorless, but avoid more than a drop or two in excess (Note 2) . Dilute with 150 cc. of water and cool !completely!. When cold, add rapidly about 30 cc. ”

“ The elements which play important parts in organic compounds are carbon, hydrogen, nitrogen, chlorine, bromine, iodine, sulphur, phosphorus and oxygen. We shall here consider the qualitative and quantitative determination of these elements.
Qualitative.—Carbon is detected by the formation of carbon dioxide, which turns lime-water milky, and hydrogen by the formation of water, which condenses on the tube, when the substance is heated with copper oxide. Nitrogen may be detected by the evolution of ammonia when the substance is heated with soda-lime. ”